F O R
C R E A T I V E
S Y N T H E S I S . . .
4 reactive organic chemicals immediately available for commercial use f-BOIYLAUNE CH 3 CH3-C-NH2 CH3 A low-viscosity, oil-soluble liquid, /-butylamine cleanly undergoes reaction to give high yields of Schiff bases, quaternary and ordinary salts, cyanamides, acetonitriles, propionitriles and others. The branched chain of ^-butylamine acts as a "reaction-regulator"—aids in controlling specific replacement either of one or of both amino hydrogens. Monosubstitution takes place easily. Under mild reaction conditions, with one mole of ethylene oxide, only traces of the di-hydroxyethylated amine are produced. Many ^-butylamine derivatives (aldimines, carbodiimides) possess unusually high stability compared with common primary amine derivatives.
i-SUlFOSALICYLIC
3,4-DICHLOROANlLINE I 00DE0YLÂNILINE C12H25
HO3S.
4
x>COOH
CI
>
CI
OH
Trifunctional 5-sulfosalicylic acid is a new and highly reactive Monsanto intermediate now commercially available for your evaluation. A tan crystalline material, this strong aromatic acid has a neutralization equivalent of 107114. It gives you three reaction sites for creative synthesis. Because of the apparent hydrogen bonding potential of its reactive groups, 5-sulfosalicylic acid offers promise as a chelating agent for metals. It is already at work as an analytical reagent for use in the determination of various metals and to detect various types of proteins.
These highly reactive compounds convert readily with good yields by reactions of the amino group. They provide direct routes to unique isocyanates, sulfenamides, ureas, Schiff bases, anilides, aromatic ethanolamines and similar products. Examples:
With acylating agents
CI
C|2"25 With sulfonyl chlorides
With acrylonitrile
^sr~^>NHS02R
CI^~^NHCH2CH2CN CI
F O R
Working samples to tankcar quantities of these four compounds are available now. Simply send your request on your company letterhead.
Monsanto
T E C H N I C A L
DATA,
( ( Please send technical data on ( (
U S E
C O U P O N
) f-Butylamlne ) 5-Sulfosalicylic Acid ) 3,4-Dichloroaniline ) Dodecylaniline
Name Monsanto Chemical Company Organic Chemicals Division Development Depf. 2805X St. Louis 66, Missouri
Company Address City
Zone
State
C&Ε Ν
63
