A Simple, Short, and Flexible Synthesis of Viridiofungin Derivatives

Addition/Correction pubs.acs.org/joc

Cite This: J. Org. Chem. 2019, 84, 6546−6546

Correction to “A Simple, Short, and Flexible Synthesis of Viridiofungin Derivatives” Stephen M. Goldup, Christopher J. Pilkington, Andrew J. P. White, Andrew Burton, and Anthony G. M. Barrett*

J. Org. Chem. 2019.84:6546-6546. Downloaded from pubs.acs.org by UNIV AUTONOMA DE COAHUILA on 05/18/19. For personal use only.

J. Org. Chem. 2006, 71 (16), 6185−6191. DOI: 10.1021/jo060931e It has come to our attention that Scheme 2 (page 6186) contained a typographic error whereby the lengths of the alkyl chains of the bromoalkene 10 and the nitrile reagent used in the synthesis of enone 4 were drawn incorrectly. The corrected Scheme 2 is shown below. Also, in the manuscript (Results and Discussion, line 2, page 6186) and Supporting Information (S5, line 6), where n-heptanenitrile was incorrectly written, noctanenitrile was in fact used. The product of the reaction 4 was correctly named as 15-hexadecen-8-one in the Supporting Information (S5, line 1) and correctly characterized. Scheme 2. Model Metathesis Reaction and Precursor Synthesisa

a

Reagents and conditions: (a) Mg, Et2O, reflux; n-C7H15CN, Et2O, 25 °C; 1 M HCl (aq), 0 °C. (b) MeOAc, LiN(i-Pr)2, THF, −78 °C; MeO2CCO2Me, −78 to 25 °C. (c) 13, In, THF−H2O (1:1), 25 °C. (d) 1 M HCl (aq), reflux. (e) Grubbs II (17) (20 mol %), PhMe, 80 °C.

Published: May 6, 2019 © 2019 American Chemical Society

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DOI: 10.1021/acs.joc.9b01172 J. Org. Chem. 2019, 84, 6546−6546