A Special Issue of CRT: Celebrating Volume 30 ... - ACS Publications

Jan 17, 2017 - Stephen S. Hecht (Editor in Chief). Masonic Cancer Center ... *2231 6th St. SE, CCRB, Minneapolis, MN 55455, USA. Phone: 612-624-7604...
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A Special Issue of CRT: Celebrating Volume 30 his issue of Chemical Research in Toxicology celebrates the beginning of Volume 30! We have asked prolific and consistent recent contributors to the journal to write Perspectives on a topic of their choice. The result is a fantastic collection of 31 Perspectives in this special issue. These papers cover a broad range of exciting topics in present day chemical toxicology including the relatively newer topics such as nanoparticles, systems toxicology, physiologically based kinetic modeling, new cell culture approaches, and markers for precision medicine as well as the more traditional areas which continue to be of high interest including idiosyncratic drug reactions, cytochrome P450 catalysis, structures and consequences of DNA and protein adducts, mechanisms of drug toxicity, metal toxicity, and environmental toxicity and carcinogenesis. The planning for this special issue began in May, 2016. I sincerely thank our authors, associate editors, and journal office staff for respecting the deadlines that have made this special issue possible. On this occasion, it was also interesting to look back at Volume 1, issue 1 of Chemical Research in Toxicology, which was begun by our Founding Editor Larry Marnett and Associate Editor Paul Hollenberg, who were both young professors at Wayne State University. Their vision for this journal and their constant dedication to excellence were critical in establishing Chemical Research in Toxicology as the leading journal in its field. The first issue contained 13 articles by leading scientists working in the area of chemical aspects of toxicity and carcinogenesis including studies on site specific modified oligonucleotides as probes for the biological effects of DNA damage, reactive intermediates from oxidative damage, structures of hemoglobin adducts, aspects of nitrosamine metabolism, bioactivation of sulfides, DNA adduct identification, and P450 catalyzed metabolism among others. These articles are still relevant and constituted a great start to the journal which ultimately grew and markedly expanded its scope while also providing the impetus for the Division of Chemical Toxicology of the American Chemical Society, where the annual Fall meetings provide a platform for stimulating presentations and discussion of the most recent science in the field. We are so grateful for the efforts of Professors Marnett and Hollenberg in this regard. The late Professor Richard Loeppky also contributed monumentally to the birth of the Division. I hope you enjoy reading this superb collection of Perspectives in celebration of Volume 30 of Chemical Research in Toxicology.

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ORCID

Stephen S. Hecht: 0000-0001-7228-1356 Notes

Views expressed in this editorial are those of the author and not necessarily the views of the ACS.

Stephen S. Hecht,* Editor in Chief



Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, United States

AUTHOR INFORMATION

Corresponding Author

Special Issue: CRT30

*2231 6th St. SE, CCRB, Minneapolis, MN 55455, USA. Phone: 612-624-7604. E-mail: [email protected]. © 2017 American Chemical Society

Published: January 17, 2017 1

DOI: 10.1021/acs.chemrestox.6b00440 Chem. Res. Toxicol. 2017, 30, 1−1