Feb 5, 2018 - The enzyme butyrylcholinesterase (BChE) and the human cannabinoid receptor 2 (hCB2R) represent promising targets for pharmacotherapy in the later stages of Alzheimer's disease. We merged pharmacophores for both targets into small benzim
The data shows the possibility to combine a small molecule with selective and balanced GPCR-activity/enzyme inhibition and in vivo activity for the therapy of AD and may help to rationalize the development of other dual-acting ligands. The Supporting
Feb 5, 2018 - The data shows the possibility to combine a small molecule with selective and balanced GPCR-activity/enzyme inhibition and in vivo activity for the therapy of AD and may help to rationalize the development of other dual-acting ligands.
Key Laboratory for Green Chemical Technology, School of Chemical Engineering & Technology, Tianjin. UniVersity, Tianjin 300072, P.R. China; School of Chemical Engineering & Technology, Hebei UniVersity of. Technology, Tianjin 300130, P.R. China; and
Sep 12, 2007 - Key Laboratory for Green Chemical Technology, School of Chemical Engineering & Technology, Tianjin University, Tianjin 300072, P.R. China; School of Chemical Engineering & Technology, Hebei University of Technology, Tianjin 300130, P.R
Jul 21, 2015 - Effects of boron doped in TiO2 at (a) interstitial site (Bint), (b) substitutional site (Bsub), and (c) combination of both the sites (Bint+sub) have been investigated experimentally and theoretically to understand the origin of enhanc
catalyzed C-H iodination reaction in the presence of a varie- ty of functionalized molecules. Under the optimal conditions. (Table 1, entry 6), amines, amides, ...
Figure 1. Formation of the junction between a bulk n-type semiconductor and an ... TiO2âCdSe,(57-60) TiO2âCdTe,(61-64) ZnOâCdSe,(65-67) ZnOâCdTe,(68) ... voltage applied between the photoelectrode and a chosen reference electrode. ..... durin
The generator well is fitted with a modified rubber stopper and delivery tube and the gases are bubbled through distilled water in adjacent wells that contain a series of acidhase indicators. (Fig. 1). The color changes observed are ... Experimental
data on the heat of fusion of silver, the results may be used to calculate LÂ°Ag, the ... If we assume, for simplicity, that theheat of fusion of silver is ... mind when Fig.
Activity: Ptable.com Investigations FOR THE TEACHER Summary In this activity, students will use the online periodic table found at www.ptable.com to investigate a number of chemistry concepts. Students will use this online resource to explore information about the elements, including historical data, physical properties, periodic trends and more. Grade Level High or middle school Objectives By the end of this lesson, students should be able to • Better understand how the periodic table is organized. • Identify several trends on the periodic table. • Classify elements by family name, group number and period number. • Understand the periodic trend of atomic radius. Chemistry Topics • Periodic Table • Periodic Trends • History • Physical Properties Time Teacher Preparation: minimal Lesson: 30-60 minutes (time will vary depending on activity chosen) Materials • Computer, tablet or mobile device (internet access is needed) • Student handouts Safety • No specific safety precautions need to be observed for this activity. Teacher Notes • This activity includes three possible student lessons: a scavenger hunt, a periodic table investigation and self-guided investigation of atomic radius. o The Scavenger Hunt: This lesson will allow students to become familiar with ptable.com. It questions students as it walks them through the many features of the website. Students will investigate a large number of topics, from physical properties to history of the elements, and will conclude the activity by watching several videos available on the website. o Periodic Table Investigation: This lesson is a self-guided introduction to the basics of the periodic table, including grouping, family names and period
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assignments. Students will also investigate common properties within a family, identify numbers of valence electrons, and create Bohr models for elements. o Atomic Radius Exploration: This lesson is designed as a self-guided investigation for students to explore the trend in atomic radius on the periodic table. Students will collect and interpret data from this interact website to support their understanding of this trend. There is an answer key provided for each of the student resources for the teacher’s reference. Teachers should be actively involved in checking the students work, reviewing answers to ensure accuracy and elaborating on concepts when needed. www.ptable.com would be a valuable resource for many activities found in the AACT resource library, such as: Periodic Trends Investigation and Element Skit.