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Spotlight on Advanced Materials Technologies, Systems, and Processes

ACS Spring National Meeting & Exposition APRIL 2, 2017 I 8:30 AM - 11:30 AM I ESPLANADE BALLROOM 301 MOSCONE CENTER, 747 HOWARD ST. I SAN FRANCISCO, CA 94103 Join us for this symposium that highlights advances by JACS contributors in research areas that align with the theme of Advanced Materials Technologies, Systems and Processes, from energy to health and beyond.

SPEAKERS Tanja Weil Max Plank Institute for Polymer Research, Germany

Shelley Minteer University of Utah

Peidong Yang UC Berkeley

Nanfeng Zheng Xiamen University, China

Marta Cerruti McGill University, Canada

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Presidential Session — Holy Grails in Chemistry

ACS Spring National Meeting & Exposition APRIL 2, 2017 I 1:20 – 4:00 PM I MARRIOTT MARQUIS SAN FRANCISCO 780 MISSION STREET I SAN FRANCISCO, CA 94103 Join us as our distinguished presenters discuss what they identify as the most important challenges facing the chemistry research of today and for the future. This special session is part of the Accounts of Chemical Research Holy Grails of Chemistry Events and Special Issue, which celebrate the most influential challenges in the field.

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Hans-Joachim Freund Fritz-Haber-Institut der Max-PlanckGesellschaft

Melanie Sanford University of Michigan

Yi Cui Stanford University

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11 Bio-Rad Laboratories ▸ 2016 instrument sales: $731 million Bio-Rad Laboratories, a provider of a broad range of life sciences research and clinical diagnostic products, saw its instrument-related sales—largely polymerase chain reaction, chromatography, and cell analysis systems—grow 5% in 2016. The year was marked by technology development agreements. For example, Bio-Rad made an equity investment in Genetic Analysis in exchange for rights to commercialize Genetic Analysis’s GA-map technology for detecting microbial imbalances in the gut. Bio-Rad also joined the Consortium for Sequencing the Food Supply Chain, which was established in 2015 by scientists from IBM Research and the food company Mars. This year, Bio-Rad and Illumina launched a system for single-cell gene-sequencing analysis. And Bio-Rad agreed to purchase RainDance Technologies, which has developed methods to study biological reactions in droplets.

sluggish market conditions in the U.S. and Europe. However, it reported that sales in Japan and the rest of Asia rose.

14 JEOL ▸ 2016 instrument sales: $653 million Japan’s JEOL expects a decline in scientific instrument sales of about 4% for the fiscal year that ends in March 2017. As for other Japanese instrument firms, the appreciating yen held back growth. JEOL is in the third part of a three-stage program begun in

2010 to revamp its business structure, set up a stable revenue base, and drive growth through “speed, difference, and change.” The company is also trying to fill a gap in the nuclear magnetic resonance spectroscopy area, which it reentered in 2013, a year before Agilent Technologies exited the market. JEOL’s newest tactic is to offer its NMR consoles as replacements for ones from other manufacturers, especially those on aging Agilent/Varian systems. JEOL suggests that upgrading magnets in this way can make NMR systems more affordable.

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12 Eppendorf ▸ 2016 instrument sales: $730 million Eppendorf is a German company that develops and sells instruments, consumables, and services for handling liquids, cells, and samples in the lab. As a private company, it does not break out its instrumentation sales, so its ranking is based on total sales of $730 million, a number that inflates its place in C&EN’s survey. The company’s sales for 2016 are an estimate reported as part of a midyear outlook presented in August. At that time, CEO Thomas Bachmann said he assumes “we will once again achieve growth for the entire fiscal year 2016 that exceeds the projected current industry average of 4%.” He attributed part of his positive view to good business development in China, where the market grew strongly during the first six months of 2016.

13 Nikon ▸ 2016 instrument sales: $699 million One hundred years ago, the company now known as Nikon began producing optical glass and instruments, including microscopes. Today, the company is reporting substantial growth in its semiconductor lithography business but not enough to offset declining sales in the digital camera area. As a result, overall sales are down, and Nikon is going through a restructuring program that will cut more than 1,000 jobs through voluntary retirements. In its instrument business, sales are estimated to decline 2%. Microscope sales were weak, the company says, owing to foreign exchange effects and

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for the testing area were down 2% in 2016 in light of what the company calls “mixed market conditions.”

22 Oxford Instruments ▸ 2016 instrument sales: $253 million In C&EN’s previous ranking of top instrumentation companies, Oxford Instruments stood out for its high rate of growth. Now it is among firms reporting big declines as its equipment sales dropped 11% for the fiscal year that ended in March 2016. Services revenues were strong, however, so total company sales fell only 5%. The company sells nanocharacterization and analysis tools to both physical and life sciences markets under a variety of brand names: Andor Technology, Asylum Research, NanoAnalysis, NanoScience, Plasma Technology, and a joint venture called Scienta Omicron. Oxford says it expects to make financial progress in fiscal 2017 by focusing on product development, customer service, and cost optimization. It also expects that the increasing role of nanotechnology will continue to yield growth for high-tech tools.

25 Qiagen ▸ 2016 instrument sales: $172 million As for other companies in the diagnostics and next-generation sequencing areas, instrumentation is just a small part of Qiagen’s sales compared with tests and consumables. Nevertheless, the company posted about 4% growth in equipment sales across all customer types and regions. Growth came from customers in academia, pharmaceuticals, and applied testing, as

well as from the acquisitions of the sample-prep firm MO BIO Laboratories and the RNA technology company Exiqon. To keep on this trajectory, Qiagen has been expanding in molecular diagnostics. The firm reports that its GeneReader NGS System received a strong reception, achieving a 10% market share for new benchtop sequencers in oncology applications. It also has sold a total of 1,750 of its QIAsymphony lab automation systems, which helped support double-digit consumables sales growth. ◾

23 Horiba ▸ 2016 instrument sales: $237 million Scientific instruments account for just 15% of sales at Japan’s Horiba and declined nearly 4% for the year. According to the company, sales of R&D instruments and systems to universities and other customers were solid in Japan and China but sluggish in Europe and the Americas, resulting in part from the yen’s appreciation. During the year, the company’s technology reached new frontiers when NASA’s Juno space probe entered Jupiter’s orbit in July. Two optical spectrometers on board use Horiba’s Jobin Yvon diffraction gratings.

24 Sartorius ▸ 2016 instrument sales: $216 million In 2016, Sartorius, a bioprocessing and lab equipment company, reported double-digit sales growth. The lab products and services division that C&EN tracks accounts for about 25% of sales, and within this, significant but undisclosed portions are lab instruments and consumables. According to the firm, the division has sharpened its strategic focus, especially among biopharmaceutical lab customers, through the 2016 acquisitions of the cell screening technology company IntelliCyt and the bioanalytical firm ViroCyt. Sartorius anticipates that sales for its lab products business this year will increase by 6 to 10%, assuming an overall stable economic environment.

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