Alkylation of amines. New method for the synthesis of quaternary

Harold Z. Sommer, and Larry L. Jackson ... Ouden, Amaia Montoya-Goñi, Dominique H. W. Hubert, Peter M. Frederik, Alex M. van Herk, and Anton L. German.

Quarternization of tertiary amines with methyl iodide. sured at 1-minintervals for 15 min and after 20, 25, and 30 min. A plot of the data is shown in Figure 1.

(1) The organic base should have solubilities ..... R. 0. Clinton and S. C. Laskowski,. 6 A. Zaku, J . Chem. SOC., 1078 (1930). f See ... B, 47, 728 (1951); Chem.

Ivan Aprahamian, Graham J. Bodwell, Jim J. Fleming, Greg P. Manning, Michael R. Mannion, Brad L. Merner, Tuvia Sheradsky, Rudolf J. Vermeij, and Mordecai ...

To the stirred solution at room ... residue was shaken with a mixture of 15 ml of pentane and 15 ml ... N-ethylnitrilium salts based on Meerwein's procedure2.

Khurshid Ayub, Rui Zhang, Stephen G. Robinson, Brendan Twamley, Richard Vaughan Williams, and Reginald H. Mitchell. The Journal of Organic Chemistry ...

Quaternary Salts from the Alkylation of Trimethylamine with t-Propargylic Chlorides1. G. F. Hennion, C. V. DiGiovanna. J. Org. Chem. , 1965, 30 (11), pp 3696– ...

Alkylation of Trimethylamine with t-Propargylic Chlorides1. G. F. Hennion and C. V. DiGiovanna. Chemical Laboratories of the University of Notre Dame, Notre ...

Alkylation of amines. General exhaustive alkylation method for the synthesis of quaternary ammonium compounds. The Journal of Organic Chemistry. Sommer ...

James Gilliam, and Charles Ashbrook of the Lilly. Research Laboratories,Indianapolis, Indiana, for the analytical determinations and to Eli Lilly and Company.