Announcements - Chemical Research in Toxicology (ACS Publications)

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Chem. Res. Toxicol. 2000, 13, 214-215

Announcements “Chemical Perspectives on Human Cancer”, Symposium in Area 8, Medicinal Chemistry Pacifichem 2000, December 16-20, 2000a Co-Organizers: P. D. Josephy, University of Guelph, Guelph, Ontario L. A. Peterson, University of Minnesota, Minneapolis, Minnesota K. Wakabayashi, National Cancer Center Research Institute, Tokyo, Japan Session 1. Carcinogens and Mutagens: Formation, Exposure, and Bioactivation Chair: K. Wakabayashi, National Cancer Center Research Institute, Tokyo, Japan 35 min talks S. S. Heckt, Ph.D. University of Minnesota, Minneapolis, MN

tentative titles Human carcinogen uptake and metabolism: Relation to cancer risk

K. Wakabayashi, Ph.D. Identification of mutagens/carcinogens in cooked food and river water National Cancer Center Research Institute, Tokyo, Japan E. G. Snyderwine, Ph.D. National Cancer Institute, Bethesda, MD

Metabolic activation and carcinogenesis of arylamines

W. R. Kusamran, Ph.D. National Cancer Institute, Bangkok, Thailand

Carcinogenic heterocyclic amines in cooked Thai foods, mutagens in drinking water, and chemopreventive potentials of some Thai vegetables

J. D. Groopman, Ph.D. John Hopkins University, Baltimore, MD

Aflatoxin specific biomarkers for cancer epidemiology and prevention

Session 2. Carcinogenesis and Mutagenesis: New Bioassays and in Vitro Assays Chair: P. D. Josephy, University of Guelph, Guelph, Ontario 35 min talks

tentative titles

E. M. Gillam, Ph.D. University of Queensland, Queensland, Australia

To be announced

P. D. Josephy, Ph.D. University of Guelph, Guelph, ON

Bacterial mutagenicity assays with recombinant human enzymes: A new tool for studying the biochemistry of carcinogen bioactivation

R. C. Moschel, Ph.D. NCI-Frederick Cancer Research and Development Center, Frederick, MD

Site specific mutagenesis by O6-substituted guanines in E. coli and human cells

M. Moriya, Ph.D. SUNY at Stonybrook, Stonybrook, NY

Mutagenesis by DNA adducts in human cells

T. Nohmi, Ph.D. National Institute of Health Sciences, Tokyo, Japan

Molecular analysis of in vivo mutations by transgenic mice gpt-delta

Session 3. DNA Adducts: Their Chemical and Biophysical Properties Chair: Lisa Peterson, University of Minnesota, Minneapolis, Minnesota 35 min talks

tentative titles

R. M. Santella, Ph.D. Columbia University, New York, NY

Carcinogen-DNA adducts in humans: Markers of exposure and risk

K. Makino, Ph.D. Kyoto University, Kyoto, Japan

DNA damage by nitric oxide

I. Yoshizawa, Ph.D. Hokkaido College of Pharmacy, Hokkaido, Japan

Characterization of estrogen-derived DNA damage

N. E. Geacintov, Ph.D. New York University, New York, NY

Structure and function of site-specific PAH diol epoxide-oligonucleotide adducts

F. P. Guengerich, Ph.D. Vanderbilt University, Nashville, TN

Polymerase interactions with carcinogen-adducted DNA

Announcements

Chem. Res. Toxicol., Vol. 13, No. 3, 2000 215

Session 4. DNA Adducts: The Biochemical Consequences of Their Formation Chair: John Essigmann, Massachusetts Institute of Technology, Cambridge Massachusetts 35 min talks

tentative titles

J. M. Essigmann, Ph.D. Massachusetts Institute of Technology, New York, NY

DNA adducts and mutations: Why do mutational spectra look the way the do?

L. A. Loeb, Ph.D. University of Washington, Seattle, WA

From DNA adducts to cancer

L. D. Samson, Ph.D. Harvard School of Public Health, Boston, MA

Cellular responses to alkylating agents

H. Kasai, Ph.D. University of Occupational and Environmental Health, Kitakyushu, Japan

Roles of 8-hydroxyguanine and 2-hydroxyadenine in mutagenesis and carcinogenesis

E. Ohtsuka, Ph.D. Hokkaido University, Hokkaido, Japan

Mutagenesis of photo-damaged DNA

a Meeting information can be found at www.acs.org/meetings/pacific2000. Abstract deadlines are April 3 for hardcopy submission and April 14 for electronic submission. Meeting dates are December 14-19, 2000, in Honolulu, HI.

TX0005006 10.1021/tx0005006 Published on Web 03/02/2000