Applications of Transition Metal Catalysis in Drug Discovery and

Oct 18, 2012 - Applications of Transition Metal Catalysis in Drug. Discovery and Development. Edited by Matthew L. Crawley, Barry M. Trost. Wiley: New...
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Applications of Transition Metal Catalysis in Drug Discovery and Development Applications of Transition Metal Catalysis in Drug Discovery and Development. Edited by Matthew L. Crawley, Barry M. Trost. Wiley: New York. 2012. 356 + xviii pp. £66.95, ISBN 978-0-470-63132-4.

T

he chapters in this multiauthor work are written by chemists from industry, mostly process chemists, and therefore, most of the book is written from a process chemistry viewpoint. After an opening introductory chapter on “Transition Metal Catalysis in the Pharmaceutical Industry”, the subjects covered are C−C Cross-Coupling, C−Heteroatom Cross-Coupling, Asymmetric Cross-Coupling, Metathesis, Synthesis of 5- and 6Membered Heterocycles, Oxidative Catalysis, and finally, Industrial Asymmetric Hydrogenation. All chapters are well-written and comprehensive with many examples from Org. Process Res. Dev. The book is highly recommended to all process chemists.



Trevor Laird, Editor AUTHOR INFORMATION

Notes

The authors declare no competing financial interest.

Published: October 18, 2012 © 2012 American Chemical Society

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dx.doi.org/10.1021/op300277x | Org. Process Res. Dev. 2012, 16, 1874−1874