Assessment of the Interaction between Aquatic Colloids and

Environ. Sci. Technol. 2007, 41, 8038–8043

Assessment of the Interaction between Aquatic Colloids and Pharmaceuticals Facilitated by Cross-Flow Ultrafiltration KHALID MASKAOUI, ANDREW HIBBERD, AND JOHN L. ZHOU* Department of Biology and Environmental Science, School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QG, U.K.

Received June 20, 2007. Revised manuscript received August 29, 2007. Accepted September 10, 2007.

Interactions between pharmaceuticals and aquatic colloids are a key process regulating their environmental fate, but poorly understood. A validated cross-flow ultrafiltration (CFUF) system was used to isolate river colloids and to determine the partition of selected pharmaceuticals between colloidal (>1 kDa but