Bayer to collaborate with PeptiDream - C&EN Global Enterprise (ACS

The Japanese drug discovery firm PeptiDream has added Bayer to the list of major drug firms with which it collaborates. Its agreement with Bayer invol...
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PHARMACEUTICALS

lium purchased from natural gas producers and the U.S. Bureau of Land Management, the caretaker of the National Helium Reserve.—ALEX TULLO

▸ Boehringer provides access to molecules

MERGERS & ACQUISITIONS

▸ Avantor completes VWR acquisition Avantor, a minnow in the laboratory supply business with about $700 million in annual sales, has completed its acquisition of VWR, a whale in the industry with $4.5 billion in sales. The combination, valued at $6.5 billion, will benefit from “deeper access to the high-growth biopharma, industrial, and applied research sectors,” says Avantor CEO Michael Stubblefield. The new firm will retain the Avantor name; the VWR name remains as a sales channel. Avantor was created in 2010 by the private equity firm New Mountain Capital through the acquisition of lab chemical maker Mallinckrodt Baker.—MARC REISCH

BIOFUELS

▸ Qantas to fuel plane with tiny seeds Early next year Qantas will fly the first biofueled flight between the U.S. and Australia, using fuel made from the seeds of Brassica carinata, a nonfood relative of the mustard plant. Fuel Services and AltAir Fuels will produce the fuel from a carinata variety developed by Agrisoma Biosciences. The

Carinata mustard seed to be grown by Australian farmers for biofuel production. companies plan to establish the water-efficient crop in Australia and hope to produce 200 million L of fuel annually by 2020. AltAir currently supplies United Airlines flights at Los Angeles International Airport with fuels made from vegetable and waste oils.—MELODY BOMGARDNER

DRUG DISCOVERY

▸ Bayer to collaborate with PeptiDream The Japanese drug discovery firm PeptiDream has added Bayer to the list of major drug firms with which it collaborates. Its agreement with Bayer involves identifying macrocyclic and constrained peptides from PeptiDream’s peptide library for use against targets selected by Bayer. Promising compounds will be optimized into therapeutic peptides or small-molecule drugs. PeptiDream will receive an up-front fee as part of the agreement and could receive as much as $1.1 billion in milestone payments. The Japanese firm has similar agreements with drugmakers including Merck & Co., Janssen, and Bristol-Myers Squibb.—JEAN-FRANÇOIS TREMBLAY

C R E D I T: AGR I S O MA BI O S C I E N CES

Business Roundup

Boehringer Ingelheim has begun offering outside scientists free access to select preclinical molecules for nonclinical investigation on an online platform called opnME.com. Most molecules are offered without intellectual property agreements. Boehringer is also offering a crowdsourcing service on the site through which scientists submit proposals for projects that can be developed with the company’s researchers. The platform follows other moves at the firm to promote collaboration, including Research Beyond Borders, a research partnership initiative, and the Boehringer Ingelheim Venture Fund.—

RICK MULLIN

INFORMATICS

▸ Roche adds data firm to diagnostics arm Roche has agreed to acquire Viewics, a laboratory analytics software firm, for an undisclosed sum. Viewics, which specializes in managing large stores of lab data from both internal and external sources, will be added to the drug firm’s Integrated Core Lab diagnostic systems business. The cloud-based Viewics system can automatically extract, cleanse, and augment data and make it accessible on devices such as smartphones, tablets, and desktop computers.—RICK MULLIN

▸ BYK, the additives and instruments business of Altana, is investing $50 million at its Gonzales, Texas, facility to expand modified phyllosilicate rheology additives. The company is also establishing a rheology modifier R&D center.

Tronox CEO Peter Johnston.

including aerospace, automotive, and energy. GeonX’s software is called Virfac for “virtual factory.”

▸ DuPont is increasing capacity to compound its Zytel nylon resins at its site in Mechelen, Belgium. The firm says demand is increasing in auto, consumer, and electronics markets.

▸ SK Capital has completed its acquisition of Perrigo’s active pharmaceutical ingredients business. The business, which operates mainly in Israel, will be called Wavelength Pharmaceuticals.

▸ Tronox has named Jeffry N. Quinn, 58, president and CEO as of Dec. 1. Quinn led Solutia from 2004 until Eastman Chemical acquired it in 2012. He succeeds interim

▸ GE Additives has acquired GeonX, a developer of software that simulates additive manufacturing, welding, machining, and heat treatment processes in industries

▸ Mayo Clinic and Evelo Biosciences are joining to develop what Evelo calls monoclonal microbials for the treatment of inflammatory diseases. Evelo will get a

license to related technology developed at Mayo. ▸ Merck & Co. has licensed T-cell-modulating biologics technology from Cue Biopharma for the treatment of autoimmune disease. Cue gets an up-front payment and could earn up to $374 million in milestones. ▸ Genentech has expanded a license agreement with Arvinas, developer of small-molecule drugs that degrade disease-causing proteins. Arvinas now could reap more than $650 million.

NOVEMBER 27, 2017 | CEN.ACS.ORG | C&EN

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