3A
Biochemistry
Published monthly by the American Chemical Society at 20th and Northampton Streets, Easton, Pennsylvania
ASSISTANT EDITOR: M I L T O N P . GORDON University of Washington, Seattle, Washington 98105
EDITOR: HANS NEURATH University of Washington, Seattle, Washington 98105
DIRECTOR OF FUNDAMENTAL JOURNALS DIVISION RICHARD H . B E L K N A P 1155 Sixteenth Street, N.W., Washington, D. C. 20036
BOARD O F ASSOCIATE EDITORS E R I C G. B A L L Department of Biological Chemistry Harvard Medical School CLINTON E . BALLOU Department of Biochemistry University of California, Berkeley
H E I N Z FRAENKEL-CONRAT The Virus Laboratory University of California, Berkeley
J O S E P H S. F R U T O N Department of Biochemistry Yale University School of Medicine
HERBERT E . CARTER Department of Chemistry and Chemical Engineering, University of Illinois R O L L I N D . HOTCHKISS Rockefeller Institute
HERMAN EISBN Department of Microbiology Washington University EDMOND H. FISCHER Department of Biochemistry University of Washington
H E N R Y A. L A R D Y Institute for Enzyme Research University of Wisconsin
ALTON M E I S T E R Department of Biochemistry Tufts University School of Medicine ESMOND E. SNELL Department of Biochemistry University of California, Berkeley H E R B E R T A. S O B E R National Cancer Institute National Institutes of Health MERTON F. UTTER Department of Biochemistry Western Reserve University BERT L. VALLEE Division of Medical Biology Peter Bent Brigham Hospital Harvard Medical School
SECRETARY OF THE BOARD: W A R R E N E . C . W A C K E R Division of Medical Biology, Peter Bent Brigham Hospital Harvard Medical School
© Copyright, 1964, b y t h e American Chemical Society. Published monthly b y the American Chemical Society at 20th and N o r t h a m p t o n Streets, Easton, Pennsylvania. Second-class postage paid at Easton, Pennsylvania. Manuscripts for publication and correspondence regard ing accepted papers should be sent t o the Editor, H a n s N e u r a t h , University of Washington, Seattle, Washington 98105. Proof, edited manuscripts and reprint orders should be sent to the Production Manager, Biochemistry, University of Washington, Seattle, Washington 98105. Advertising Office: Reinhold Publishing 430 Park Avenue, N e w York 22, Ν . Υ .
Corporation,
Subscriptions should be renewed promptly, to avoid a break in your series. Claims for missing numbers will n o t be allowed (1) if received more than sixty days from date of issue plus time normally required for postal delivery of journal and claim, (2) if loss was due t o failure of notice of change in address to be received before the date specified in the preceding para graph, or (3) if t h e reason for t h e claim is "missing from files." Subscription rates for 1964: t o members, $13.00 per year; t o non-members, $26.00 per year. Postage to countries in t h e Pan-American Union, $0.90; Canadian, $0.50; all other countries, $1.50.
Business and Subscription Information
Single copies: for current year $2.50. Postage, single copies: to Canada and countries in t h e Pan-American Union, $0.15; all other, $0.20. R a t e s for back issues are available from the Special Issues Sales Department, 1155 Sixteenth St., N . W . , Washington, D . C. 20036.
Remittances and orders for subscriptions and for single copies, notices of changes of address and n e w professional connections, and claims for missing numbers should be sent to the Subscription Service Department, American Chemical Society, 1155 Sixteenth Street, N . W . , Washington, D . C. 20036. Changes of address for this journal must be received four weeks before t h e first issue is t o g o t o t h e new address. Such notification should include b o t h old and new addresses and zip code. Please enclose a mailing label from a copy of one of your A C S publications w i t h your notification.
Publications of the American Chemical Society include: Analytical Chemistry, Biochemistry, Chemical Abstracts, CA Section G r o u p i n g s , Chemical and Engineering News, Chem ical Reviews, Chemical Titles, Chemistry, Industrial and Engineering Chemistry, Inorganic Chemistry, Journal of Agricultural and Food Chemistry, Journal of the American Chemical Society, Journal of Chemical Documentation, Jour nal of Chemical and Engineering Data, Journal of Medicinal Chemistry, The Journal of Organic Chemistry, a n d The Journal of Physical Chemistry. R a t e s on request.
T h e American Chemical Society and the Editors of Biochemistry assume n o responsibility for t h e statements and opinions advanced b y contributors t o this Journal.