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Biocompatibility and biodegradation of a low elastic modulus Ti-35Nb-3Zr alloy: Nanosurface engineering for enhanced biodegradation resistance Ohan Mazigi, Bobby Kannan Mathan, Jia Xu, Han-Cheol Choe, and Qingsong Ye ACS Biomater. Sci. Eng., Just Accepted Manuscript • DOI: 10.1021/acsbiomaterials.6b00563 • Publication Date (Web): 27 Feb 2017 Downloaded from http://pubs.acs.org on March 5, 2017
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ACS Biomaterials Science & Engineering
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Biocompatibility and degradation of a low elastic modulus Ti-35Nb-3Zr
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alloy: Nanosurface engineering for enhanced degradation resistance
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Ohan Mazigi a, M. Bobby Kannan a*, Jia Xu b, Han-Cheol Choe c, Qingsong Ye d
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a
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Biomaterials and Engineering Materials (BEM) Laboratory
College of Science and Engineering, James Cook University, 1 James Cook Drive, Townsville, Queensland 4811, Australia
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College of Medicine and Dentistry, James Cook University, 14-88 McGregor Road, Cairns, Queensland 4878, Australia c Department of Dental Materials, Chosun University, 375 Seosuk-dong, Dong-gu,
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Gwangju 501-759, South Korea
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School of Dentistry, The University of Queensland, 288 Herston Road, Brisbane, Queensland 4006, Australia
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ABSTRACT: In this study, the biocompatibility and degradation behavior of a low elastic
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modulus Ti-35Nb-3Zr alloy were investigated and compared with that of the conventional
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orthopedic and dental implant materials, i.e., commercially pure titanium (Cp-Ti) and Ti-
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6Al-4V alloy. The biocompatibility test results suggested that cells proliferate equally well
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on Ti-35Nb-3Zr and Cp-Ti. The degradation rate of Cp-Ti and Ti-6Al-4V was ~68%
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(p
