Bioinspired Polymerization of Dopamine to Generate Melanin-Like

Feb 14, 2011 - ACS Sustainable Chemistry & Engineering 2018 6 (2), 2324-2333 ... Industrial & Engineering Chemistry Research 2018 57 (2), 590-599 ...
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ARTICLE pubs.acs.org/Biomac

Bioinspired Polymerization of Dopamine to Generate Melanin-Like Nanoparticles Having an Excellent Free-Radical-Scavenging Property Kuk-Youn Ju, Yuwon Lee, Sanghee Lee, Seung Bum Park, and Jin-Kyu Lee* Department of Chemistry, Seoul National University, Seoul 151-747, South Korea

bS Supporting Information ABSTRACT: Melanin-like nanoparticles were synthesized with size control through neutralization of dopamine hydrochloride with NaOH, followed by spontaneous air oxidation of dopamine. Although the particle characteristic of natural melanins was understood to be significantly affected by the biological and structural environment, melanin-lke nanoparticles can be realized through the chemical reactions only. Melanin-like nanoparticles that are