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BIOTECHNOLOGY PROGRESS
March/April 1994
VOLUME 10, NUMBER 2
Copyright 1994 by the American Chemical Society and the American Institute of Chemical Engineers BIPRET 10(2) 129-236 (1994)
ISSN 8756-7938
EDITOR J E R O M E S. SCHULTZ Center for Biotechnology and Bioengineering University of Pittsburgh Pittsburgh, Pennsylvania 15219 Phone: (412) 383-9712 Fax: (412) 383-9710 ASSOCIATE EDITOR, REVIEWS MICHAEL C. FLICKINGER Institute for Advanced Studies in Biological Process Technology University of Minnesota St. Paul, Minnesota 55108 Phone: (612) 624-9706 Fax: (612) 625-1700 ADVISORY BOARD Fredric Bader Auto Immune James Bailey ΕΤΗ, Zurich Kenneth Bischoff University of Delaware Bruce Dale Texas A&M University Elmer Gaden, Jr. University of Virginia John Gerlt University of Maryland Juan Hong University of California—Irvine Rakesh Jain Harvard Medical School John Jost Genentech, Inc. Alexander Klibanov Massachusetts Institute of Technology Michael Ladisch Purdue University Douglas Lauffenburger University of Illinois, Urbana-Champaign Daryl Lund Rutgers University Janice Phillips Lehigh University Sharon Shoemaker University of California—Davis Michael Shuler Cornell University Gregory Stephanopoulos Massachusetts Institute of Technology JoAnn Stubbe Massachusetts Institute of Technology James Swartz Genentech, Inc. Elizabeth Theil North Carolina State University K. Venkat Phyton Catalytic, Inc Henry Wang University of Michigan Howard Weetall National Institute of Science and Technology
ARTICLES
129
Synthesis of 0-Ionone in an Aldehyde/Xanthine Oxidase/^-Carotene System Involving Free Radical Formation Aurélie Bosser and Jean Marc Belin*
134
Gene Structural Analysis and Expression of Human Renal Dipeptidase Susumu Satoh, Kazuyuki Ohtsuka, Yuriko Keida, Chihiro Kusunoki, Yoshiyuki Konta, Mineo Niwa,* and Masanobu Kohsaka
141
Ethanol Production in Baker's Yeast: Application of Experimental Perturbation Techniques for Model Development and Resultant Changes in Flux Control Analysis Paul M. Schlosser, Gerard Riedy, and James Έ. Bailey*
155
Production of Oryzacystatins I and II in Escherichia coli Using the Glutathione S-Transferase Gene Fusion System Dominique Michaud, Binh Nguyen-Quoc, and Serge Yelle*
160
Effect of Glucose on the Expression Parameters of Recombinant Protein in Escherichia coli during Batch Growth in Complex Medium Xiaoli Li and Kenneth B. Taylor*
165
Effects of Abrupt and Gradual Osmotic Stress on Antibody Production and Content in Hybridoma Cells That Differ in Production Kinetics Sridhar Reddy and William M. Miller*
174
Competitive Immunosorbent Assays for Biotin Using Bifunctional Unilamellar Vesicles Matthew A. Jones, Peter K. Kilpatrick, and Ruben G. Carbonell*
187
Solvent Selection and Productivity in Multiphase Biotransformation Systems Harish K. Santhanam and Gina S. Shreve*
193
Flow-Cytometric Determination of the Respiratory Activity in Growing Saccharomyces cerevisiae Populations Danilo Porro,* Carla Smeraldi, Enzo Martegani, Bianca Maria Ranzi, and Lilia Alberghina
198
Viable Cell Recycle with an Inclined Settler in the Perfusion Culture of Suspended Recombinant Chinese Hamster Ovary Cells James A. Searles, Paul Todd, and Dhinakar S. Kompala*
