BOOKS RECEIVED Analytical Method Development and Validation Michael E. Swartz and Ira S. Krull Marcel Dekker 270 Madison Ave. New York, NY 10016 1997, 92 pp., $35
Topics include basics; method validation according to the USP and the International Conference on Harmonization; system suitability; method validation protocol; method transfer and revalidation; and method development, optimization, and validation approaches. A bibliography is included. Handbook of Drug Analysis: Applications in Forensic and Clinical Laboratories Ray H. Liu and Daniel E. Gadzala American Chemical Society 1155 16th St., NW Washington, DC 20036 1997, 367 pp., $129.95
Topics covered in this book include characteristics of abused drugs, sample pretreatment, color tests, TLC, immunoassay, chromatography, molecular spectrophotometry, NMR, MS, developing analytical technologies, sample differentiation, and interpreting test results. Appendices and an index are included. Handbook of Instrumental Techniques for Analytical Chemistry Frank Settle, Ed. Prentice Hall One Lake St. Upper Saddle River, NJ 07458 1997, 994 pp., $95
The 51 chapters in this volume are divided into eight sections. The first section
covers inorganic and organic sample preparation, quantitative measurements, managing information, and lab automation. The remaining sections cover separation methods, quantitative and qualitative optical spectroscopy, MS, electroanalytical techniques, microscopic and surface analysis, and polymer analysis. A glossary and index are included. Robustness of Analytical Chemical Methods and Pharmaceutical Technological Products Margriet M.W.B. Hendriks, Jan H. de Boer, and Age K. Smilde, Eds. Elsevier Science P.O. Box 945 New York, NY 10159-0945 1996, 345pp,, $243.75
The eight chapters in this book cover robustness, stability, and response-surface methodology; robustness and ruggedness in analytical chemistry; incorporating robustness in optimization procedures; tests for ruggedness; stabilizing a TLC separation of street drugs; liquid-liquid extraction of drugs; and using factorial design to evaluate physical stability of tablets. An index is included. Electrospray Ionization Mass Spectrometry: Fundamentals, Instrumentation, and Applications Richard B. Cole John Wiley & Sons 605 Third Ave. New York, NY 10158 1997, 577 pp., $89.95
The 15 chapters in this book cover fundamentals, ESI on quadrupole and magnetic sector instruments, ESI TOFMS, ESI quadrupole ion-trap MS, ESI-FT-
ICRMS, LC/MS, CE/MS, and applications such as peptides, proteins, nucleic acids, carbohydrates, lipids, drug metabolism and pharmacokinetics, and inorganic and organometallic complexes. An index is included. Time-of-Flight Mass Spectrometry: Instrumentation and Applications in Biological Research Robert J. Cotter American Chemical Society 1155 16th St.. NW Washington, DC 20036 1997, 326 pp., $62.95
Topics covered in this book include TOF, SIMS, pulsed extraction, continuous ionization, ion storage, tandem TOF, and hybrid instrumentation; reflectrons; plasma desorption MS; laser desorption; MALDI product ion mass spectra from reflectron instruments; peptides; proteins; glycoproteins; oligonucleotides; and the human genome. An index is included. Static Headspace-Gas Chromatography: Theory and Practice Bruno Kolb and Leslie Ettre John Wiley & Sons 605 Third Ave. New York, NY 10158 1997, 298, $79.95
The nine chapters in this book include introductory information, theory, technique, sample handling, quantitative and qualitative analysis, method development, nonequilibrium static headspace analysis, and special measurements. A list of acronyms and symbols, and compound and subject indexes are included.
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