Bridging the performance gap from analytical to preparative - C&EN

Nov 1, 2004 - Advertisements that appeared within the print issues of Chem. Eng. News have been included in the C&EN Archives to provide a ...
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Bridging the performance gap from analytical to preparative Efficient Target Isolation from Complex Crudes

Accurate Scale-up on Sunfire™ columns in 0.1% TFA Compounds: 1. 8-Bromoguanosine 2. Acetanilide 3. Hydrocortisone 4. 6o-AAefhyl-17a-hydroxyprogeslerone

Today's drug discovery environment demands the rapid isolation of high purity compounds with minimal chromatographic development. Waters Optimum Bed Density (OBD™) preparative columns have been engineered to deliver consistent column-to-column performance, unmatched column lifetime with DMSO sample diluents, maximum loadability in simple mobile phase conditions, accurate scalability and high peak capacity.

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19 χ 100 mm, 5 μηη Injection Volume: 1020 μι DMSO Total Mass Load: 115.7mg

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scale-up calculator.

For Purification ν Confidence

4 . 6 χ 100 mm, 5 pm Injection Volume: 6 0 μι DMSO Total Load: 6.9 mg

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Waters OBD™ columns are available in all of Waters innovative chemistries designed to meet every synthesis challenge.

www.waters.com/bridgethegap

5. 3-Aminofluoranthene 6. 2-Bromofluorene 7. Perylene

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