Monograph pubs.acs.org/doi/book/10.1021/acsreagents
Brucine Sulfate Heptahydrate (2,3-Dimethoxystrychnidin-10-one Sulfate Heptahydrate) Part 4, Monographs for Reagent Chemicals: General Descriptions, Specifications, and Tests eISBN: 9780841230460 Tom Tyner Chair, ACS Committee on Analytical Reagents James Francis Secretary, ACS Committee on Analytical Reagents
ABSTRACT This monograph for Brucine Sulfate Heptahydrate provides, in addition to common physical constants, a general description including typical appearance, applications, change in state (approximate), and aqueous solubility. The monograph also details the following specifications and corresponding tests for verifying that a substance meets ACS Reagent Grade specifications including: Sensitivity to Nitrate, Clarity of Solution, Loss on Drying, and Residue after Ignition.
(C23H26N2O4)2 • H2SO4·7H2O
Formula Wt 1013.12
CAS No. 5787-00-8
GENERAL DESCRIPTION Typical appearance . . . . . . . . Applications . . . . . . . . . . . . . Change in state (approximate) . Aqueous solubility . . . . . . . . .
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colorless or white solid determination of nitrate melting point, 180 °C, decomposes 1 g in 75 g of cold water, 10 g of hot water
SPECIFICATIONS Sensitivity to nitrate . . . . . . . . . . . . . . . . . . Passes test
© 2017 American Chemical Society
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DOI:10.1021/acsreagents.4065 ACS Reagent Chemicals, Part 4
ACS Reagent Chemicals
Monograph
pubs.acs.org/doi/book/10.1021/acsreagents
Maximum Allowable Clarity of solution . . . . . . . . . . . . . . . . . . . . Passes test Loss on drying . . . . . . . . . . . . . . . . . . . . . . 13.0% Residue after ignition. . . . . . . . . . . . . . . . . . 0.1%
TESTS Sensitivity to Nitrate
For the Determination of Sensitivity to Nitrate
Te s t S o l u t i o n s 1 , 2 , 3 , a n d 4 . Prepare a sample solution by dissolving 0.6 g in dilute sulfuric acid (2:1), as described in Method 1 in [Part 2: Colorimetry and Turbidimetry; Nitrate; Procedure for Nitrate, Method 1 (Brucine Sulfate)]. Place 50 mL of this sample solution in each of four test tubes, and add nitrate ion (NO3) to each as follows: No. 1, none; No. 2, 0.01 mg; No. 3, 0.02 mg; and No. 4, 0.03 mg.
Heat the four test tubes in a preheated (boiling) water bath for 10 min. Cool rapidly in an ice bath to room temperature. Set a spectrophotometer at 410 nm and, using 1 cm cells, adjust the instrument to read 0 absorbance with solution 1 in the light path. Determine the absorbance for solutions 2, 3, and 4 at this adjustment, using similar cells. The absorbances for solutions 2, 3, and 4 should not be less than 0.025, 0.050, and 0.075, respectively, and the plot of absorbances versus nitrate concentrations should be linear.
Clarity of Solution Dissolve 1 g in 100 mL of water, and digest in a covered beaker on a hot plate (~100 °C) for 1 h. The solution should be as colorless and clear as an equal volume of water.
Loss on Drying Weigh accurately about 1 g, and dry on a tared, preconditioned dish at 105 °C for 6 h.
Residue after Ignition [Part 2: Gravimetric Methods; Residue after Ignition]. Ignite 1.0 g. Omit the addition of sulfuric acid.
© 2017 American Chemical Society
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DOI:10.1021/acsreagents.4065 ACS Reagent Chemicals, Part 4
