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Chapter 20

California Wine Use Leads to Improvement of Thrombogenic and Peroxidation Risk Factors in Hyperlipemic Subjects

Downloaded by RUTGERS UNIV on December 28, 2017 | http://pubs.acs.org Publication Date: March 1, 1997 | doi: 10.1021/bk-1997-0661.ch020

Tom R . Watkins and Marvin L. Bierenbaum Kenneth L. Jordan Heart Foundation, 48 Plymouth Street, Montclair, NJ 07042

Recently, protective benefits have been attributed to moderate wine consumption, particularly in the case of cardiovascular disease. To test the efficacy of wine on known risk factors, 180 ml/d of either a California Chardonnay or Cabernet was given to twenty hyperlipemic subjects. In this three-month cross-over design, serum lipids, peroxidized lipid, selected vitamins and platelet aggregation were compared before and after red and white wine consumption. No major change occurred in serum lipids as a result of daily wine usage, though Chardonnay consumption led to a mild decrease in serum L D L cholesterol fraction that approached significance (p