Environ. Sci. Technol. 1992, 26, 999-1004
Chemical Characterization of Mutagenic Fractions of Particles from Indoor Coal Combustion: A Study of Lung Cancer in Xuan Wei, China Jane C. Chuang" Atmospheric Science and Applied Technology, Batteiie Columbus Operations, Columbus, Ohio 4320 1-2693
Stephen A. Wise Organic Analytical Research Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899
Shoren Cao Institute of Environmental Health and Engineering, Beijlng, China
Judy L. Mumford Health Effects Research Laboratory, US. Environmental Protection Agency, Research Triangle Park, North Carolina 277 11 ~~
In the rural Xuan Wei County, Yunnan Province, lung cancer mortality rates for women are among the highest in China. Most of these women are nonsmokers, and studies have shown that lung cancer in Xuan Wei is associated with domestic use of smoky coal under unvented conditions. The objective of this study is to determine the chemical constituents that may be linked to the high lung cancer rates in Xuan Wei using the bioassay-directed fractionation method. Ten high-volume filter samples (
