5/20/2013
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Green Chemistry Business Plan Workshop - June 19, 2013 At the 17th Annual Green Chemistry and Engineering Conference In North Bethesda, Maryland (just outside Washington, DC) Learn how to craft the perfect pitch and successfully attract venture capital investment! Schedule
Topic
9:30 – 10:45
Business Plan Panel Discussion
10:45 – 11:15
How to develop a Business Plan
11:15 – 11:45
What is a Term Sheet
11:45 – 12:15
What needs to be in a Pitch
12:15 – 3:30
Lunch on your own + Conference Networking
3:30 – 5:30
Business Plan Pitches
For more information please visit
http://gcande.org/green-business-plan-workshop 6
3
5/20/2013
Upcoming ACS Webinars™ www.acswebinars.org Thursday, April 25, 2013
Protect Your IP: A Guide to the Newly Implemented Patent Laws Mr. Michael Brodowski, Burns & Levinson LLP Dr. David Harwell, ACS Career Management and Development
Thursday, May 9, 2013
Sous Vide Cooking Chemistry Mr. Douglas Baldwin, Author Dr. Sara Risch, Director of R&D and QA for Popz Europe
Contact ACS Webinars™ at
[email protected] 7
Acknowledgement:
The 2013 Chemical Entrepreneurship Series is co-produced by UC San Diego von Liebig Entrepreneurism Center.
http://www.jacobsschool.ucsd.edu/vonliebig Contact ACS Webinars™at
[email protected] 8
4
5/20/2013
Upcoming ACS Webinars™ www.acswebinars.org
“Everyone today must think like an entrepreneur whether it’s in your own business, a large corporation or a nonprofit organization.”
Continues Thursday, May 16, 2013 @ 2PM ET Learning how to develop the next big start-up has never been so entertaining! ACS members who attend 7 out of 9 sessions get a Certificate of Completion.
Contact ACS Webinars™ at
[email protected] 9
Chance to win Neil’s Book: How could graduate programs better prepare their students for entrepreneurism?
Share with us on (Search for acswebinars)
or by email at
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5
5/20/2013
ACS WEBINARS™ April 18, 2013
2013 Chemical Entrepreneurship Series: From Academia to Entrepreneurship
Dr. Magda Marquet Founder, Althea Technologies
Barbara Bry COO, Blackbird Ventures
Dr. Mike Chi CTO, Cognionics, Inc.
Download the presentation and slides ONE WEEK after webinar: http://acswebinars.org/chemical-entrepreneurship-2013 Co-produced with UC San Diego’s von Liebig Center
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Magda Marquet, Ph.D. Co-Chair & Co-Founder
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Mission Statement “We partner with our customers to accelerate the introduction of innovative therapeutics and vaccines to the global market by providing the highest quality, value added product development and manufacturing services.”
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Company Profile • Recently acquired by Ajinomoto • 250 Employees • >75,000 Sq. Ft. of Manufacturing, Laboratory and Warehouse Space • >110 Active Clients in 2012
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History & Milestones 1998
2000
2003
2008
Founded in San Diego by Magda Marquet, Ph.D. and Francois Ferre, Ph.D.
2009
2010 2011
1st Commercial Customer Signed Acquisition of WindRose Analytica Protein Analytics Services
Plasmid kits, biomarkers, and gene quantification
cGMP Biologics Manufacturing
AltheaDx Spun-Out
cGMP Fill Finish Manufacturing
Large Scale Facility Completed
2012
Successful PAI Inspection of Large Scale Commercial Facility
Campus Expansion brought Analytics to San Diego 2nd Commercial Product Signed
Acquired Altus Pharmaceuticals’ Protein Crystallization Technology
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Leadership Team Seasoned professionals with extensive experience and proven track records. Corporate Leader
Title
Rick Hancock
President & CEO
Martha Demski
CFO
Chris Duffy
Senior VP Operations
EJ Brandreth
Senior VP Quality & Regulatory Affairs
Jack Wright
VP Sales & Marketing
Melissa Rosness
Senior Director, Biologics & Business Processes
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Client Experience Clients range from virtual, small and large biotech/pharma, international, government and universities.
• •
Seven Clients from Top 10 Biotech/Pharma >350 Clients and 600+ Client Projects
Proven track record of cGMP manufacturing success.
• • •
Cell Banks: >300 Biologics: >160 Protein & Plasmid GMP Lots Fill/Finish: >500 Projects / >1,700 GMP Lots
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Services & Solutions Phase 1 Pre-clinical Preclinical
Clinical Trials Phase 2 I, II, III
Phase 3
Commercial Commercial
Analytical Methods Development & Validation
Product Development
Reference Standard Qualification & Product Characterization Comparability Studies Stability & Release Testing Process Development/Optimization
Drug Substance Drug Product Manufacturing
Process Characterization/Validation
Protein & Plasmid DNA Production Complex Formulation Vial & Syringe Filling Lyophilization
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Althea Crystal Technology Proprietary Protein Crystal Formulations • • •
Sustained Release High-Concentration cGMP Capability • •
Multiple Lots Produced Equipment and Skids On-Site
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Regulatory History • Average 4-6 Customer Audits per Month • 28 QP Inspectors (Germany, UK, Belgium, France) • FDA Inspection – 2005, 2008, 2011, 2012 • PAI: 2 Commercial Products – April 2011 • EMA & Health Canada Inspection – Expected 2013 • FDB Licensed (California) – Current • Type II DMF & Type V BMF • Site Master File 20
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Value-Added Althea Quality • Continuous Improvement Program: Trending, Quality Metrics, Management Review • PDA, ISPE Leadership Assures Leading-Edge Policies • Broad Base of GMP Qualified Vendors – Reduces Material Procurement Risks • Multinational Compliance Program – Maximizes Clinical Flexibility • Internal Calibration, Validation, QC Chem, QC Micro, Doc Control
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Why Althea? • Experience • Flexibility • Scalability • Customized Solutions • Reliability
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Thank You! We Look Forward To A Successful Partnership
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Do you need industry experience to be an successful entrepreneur?
• No, if you got it…you got it! • Yes, definitely • Maybe, whatever my advisor says
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5/20/2013
January 18th, 2011
Cognionics, Inc.
Yu M. Chi Chief Technology Officer
UCSD Graduate Student (Ph.D. Degree 2011) Department of Electrical and Computer Engineering Integrated Systems Neuroengineering Laboratory
[email protected] January 18th, 2011
About Cognionics UCSD spin-off from Prof. Gert Cauwenberghs’ research Started operations in summer 2011 Currently 7 employees on payroll 2000 sq. ft. R&D office in San Diego First commercial licensing deal signed in 2012 First commercial product will be on the market mid 2013
Support and funding via SBIR grants and research contracts from:
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5/20/2013
January 18th, 2011
Motivation ECG/EEG: -Simple to build -Inexpensive to use -Non-invasive for the subject -Widely used in clinical and research settings -Diagnostically useful information
Today’s ECG/EEG sensors, however: -Require adhesives and skin-irritating gels -Number one patient complaint against mobile ECG/EEG devices -Need for new, patient-friendly, sensor technologies -Large usability barrier outside of laboratory environments
January 18th, 2011
Cognionics Non-contact Sensors
Many different companies working in this space, yet none have achieved widespread market acceptance. All have significant issues with poor signal quality. There is no technology that can achieve a good signal without the use of gels, through clothing and on freely moving subjects. Cognionics has expertise and a new proprietary technology for high-quality, non-contact, throughclothing sensor. It is based on a patent-pending amplifier design from UCSD that overcomes many of the practical limitations in this field.
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5/20/2013
January 18th, 2011
Cognionics Dry Contact Sensors Conventional EEG electrodes suffer from similar usability problems as their ECG counterparts – but on much larger scale (22 to 256 sensors vs. 10).
Prior dry electrode designs used hard metal pins which were uncomfortable, potentially unsafe in ambulatory use
g.tec
Cognionics Flexible Dry Electrode:
January 18th, 2011
UCSD Assistance
Advisor: Michael Elconin (now C.E.O.) Development of market research and business plans Assistance with securing university intellectual property Critical outsider’s feedback and sanity check (!) on the technology Assistance with business launch and funding strategy
Start-up business boot-camp for the engineering graduate student Opportunity to practice pitches and test business plans Many many events for learning, publicity and networking Provided $45.5K of start-up funds and services to launch the company
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5/20/2013
January 18th, 2011
Company Milestones First R&D lab in apartment bathroom – 10/2010 Officially started operations – 6/2011 Awarded DARPA research contract – 10/2011 Awarded NASA SBIR – 11/2011 First Licensing agreement – 5/2012 Awarded NIH SBIR – 7/2012 Moved into 2000 sq. ft. office – 12/2012 Selected for DARPA SBIR – 3/2013 About to first distributorship agreement with product release mid-2013 7 patent applications filed
Do you feel your grad training has prepared you to become a successful entrepreneur ?
• No and therefore I’m tuning into this webinar. • Yes, but I did not advantage of all the resources. • Yes, all I need is $.
32
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5/20/2013
ACS WEBINARS™ April 18, 2013
The Keyword is…
FISH HOOK
ACS members who attend 7 out of 9 sessions get a Certificate of Completion.
33
ACS WEBINARS™ April 18, 2013 2013 Chemical Entrepreneurship Series: From Academia to Entrepreneurship
Dr. Magda Marquet Founder, Althea Technologies
Barbara Bry COO, Blackbird Ventures
Dr. Mike Chi CTO, Cognionics, Inc.
Download the presentation and slides ONE WEEK after webinar: http://acswebinars.org/chemical-entrepreneurship-2013 Co-produced with UC San Diego’s von Liebig Center
34
17
5/20/2013
Acknowledgement:
The 2013 Chemical Entrepreneurship Series is co-produced by UC San Diego von Liebig Entrepreneurism Center.
http://www.jacobsschool.ucsd.edu/vonliebig Contact ACS Webinars™at
[email protected] 35
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5/20/2013
Upcoming ACS Webinars™ www.acswebinars.org Thursday, April 25, 2013
Protect Your IP: A Guide to the Newly Implemented Patent Laws Mr. Michael Brodowski, Burns & Levinson LLP Dr. David Harwell, ACS Career Management and Development
Thursday, May 9, 2013
Sous Vide Cooking Chemistry Mr. Douglas Baldwin, Author Dr. Sara Risch, Director of R&D and QA for Popz Europe
Contact ACS Webinars™ at
[email protected] 37
Upcoming ACS Webinars™ www.acswebinars.org
“Everyone today must think like an entrepreneur whether it’s in your own business, a large corporation or a nonprofit organization.”
Continues Thursday, May 16, 2013 @ 2PM ET Learning how to develop the next big start-up has never been so entertaining! ACS members who attend 7 out of 9 sessions get a Certificate of Completion.
Contact ACS Webinars™ at
[email protected] 38
19
5/20/2013
Chance to win Neil’s Book: How could graduate programs better prepare their students for entrepreneurism?
Share with us on (Search for acswebinars)
or by email at
[email protected] Contact ACS Webinars™ at
[email protected] 39
Green Chemistry Business Plan Workshop - June 19, 2013 At the 17th Annual Green Chemistry and Engineering Conference In North Bethesda, Maryland (just outside Washington, DC) Learn how to craft the perfect pitch and successfully attract venture capital investment! Schedule
Topic
9:30 – 10:45
Business Plan Panel Discussion
10:45 – 11:15
How to develop a Business Plan
11:15 – 11:45
What is a Term Sheet
11:45 – 12:15
What needs to be in a Pitch
12:15 – 3:30
Lunch on your own + Conference Networking
3:30 – 5:30
Business Plan Pitches
For more information please visit
http://gcande.org/green-business-plan-workshop 40
20
5/20/2013
If you enjoyed this ACS Webinar today… please support the program!
www.join.acs.org
Find the many benefits of ACS membership! 41
ACS Webinars™ does not endorse any products or services. The views expressed in this presentation are those of the presenter and do not necessarily reflect the views or policies of the American Chemical Society.
Contact ACS Webinars™at
[email protected] 42
21
5/20/2013
Upcoming ACS Webinars™ www.acswebinars.org Thursday, April 25, 2013
Protect Your IP: A Guide to the Newly Implemented Patent Laws Mr. Michael Brodowski, Burns & Levinson LLP Dr. David Harwell, ACS Career Management and Development
Thursday, May 9, 2013
Sous Vide Cooking Chemistry Mr. Douglas Baldwin, Author Dr. Sara Risch, Director of R&D and QA for Popz Europe
Contact ACS Webinars™ at
[email protected] 43
22
