For a much'iieeded, molecular focus on the toxicological effects of chemical agents
Chemical Research π » ίΤΓτττη ΓΤΤΓΤΪ Published bimonthly by the American Chemical Society Editor: Lawrence J. Marnett, Vanderbilt University Associate Editors: Fred P. Guengerich, Vanderbilt University Paul F. Hollenberg, Wayne State University
In primary research reports, Chemical Research in Toxicology covers:
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• Structure elucidation of novel toxic agents; • Chemical and physical studies on chemical agents that provide insight into their mode or mechanism of action; • Experimental and theoretical investigations of the interaction of toxic chemicals with biological macromolecules and other biological targets; • A range of topics which includes toxicity, teratogenicity, mutagenicity, carcinogenicity, neurotoxicity, and immunotoxicity.
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Guided by an esteemed, international editorial advisory board, Chemical Research in Toxicology delivers peer-reviewed articles and invited reviews, communications and perspectives, such as these:
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A Metabolically Competent Human Cell Line Expressing Five cDNAs Encoding Procarcinogen'Activating Enzymes: Application to Mutagenicity Testing. C.L Crespie, F.J. Gonzalez, D.T. Steimel, T.R. Turner, H.V. Gelvoin, B.W. Penman, and R. Langenbach. Carbamoylation of Peptides and Proteins In Vitro by S-fiV-Mediy/carfca/noy/j glutathione and S~(N-Methykarbamoyl) cysteine, Two Electrophilic S-Linked Conjugates of Methyl Isocyanate. P.G. Pearson, J.G. Slatter, M.S. Rashed, D-H. Han, and T.A. Billie. Identification of Epoxide-and QuinoneOerived Bromobenzene Adducts to Protein Sulfur Nucleophiles. D.E. Slaughter and R.P. Hanzlik. Mass Spectrometric Analysis of TobaccO'Speciûc Nitrosamine-DNA Adducts in Smokers andNonsmokers. P.G. Foiles, S.A. Akerkar, S.G. Carmella, M. Kagan, G.D. Stoner, J.H. Resau, and S.S. Hecht.
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CRT reviews all articles promptly, and upon acceptance, publishes in a timely manner. For complete information on manuscript submission, please contacr Lawrence J. Marnett, Department of Biochemistry & Center for Molecular Toxicology, School of Medicine, Vanderbilt University, Nashville, TN 37232-0146. Phone: 615-343-7328. Fax: 615-343-7534.
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962 A · ANALYTICAL CHEMISTRY, VOL. 64, NO. 20, OCTOBER 15, 1992
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