For an international, molecular focus on the toxicological effects of chemical agents
Chemical Research in Toxicology Published bimonthly by the American Chemical Society Editor: Lawrence J. Marnett Department of Biochemistry & Center for Molecular Toxicology School of Medicine Vanderbilt University Nashville, TN 37232 (615) 343-7328
Associate Editors: Frederick P. Guengerich Vanderbilt University Paul F. Hollenberg Wayne State University
1993 Subscription Information In primary research reports, Chemical Research in Toxicology covers:
Chemical Research in Toxicology is published by t h e A m e r i c a n C h e m i c a l Society. O n e v o l u m e per year. 1993 V o l u m e 6 1993 I S S N 0 8 9 3 - 2 2 8 X .
• Structure elucidation of novel toxic agents; • Chemical and physical studies on chemical agents that provide insight into their mode or mechanism of action;
Chemical Research Toxicology
• Experimental and theoretical investigations of the interaction of toxic chemicals with biological macromolecules and other biological targets; • A range of topics which includes toxicity, teratogenicity, mutagenicity, carcinogenicity, neurotoxicity, and immunotoxicity.
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uided by an esteemed, international editorial advisoty board, Chemical Research in Toxicohgy delivers peer-reviewed articles and invited reviews, communications and perspectives, such as these: jij,
• A Metabolically Competent Human Cell Line Expressing Five cDNAs Encoding Procarcinogen-Activating Enzymes: Application to Mutagenicity Testing. C.L, Crespie, F.J. Gonzalez, D.T. Steimel, T.R. Turner, H.V. Gelvoin, B.W. Penman, and R. Langenbach. ι Carbamoylation of Peptides and Proteins In Vitro fry S-(N-Methylcarbamoyl) glutathione and S-(N-Methylcarbamoyl) cysteine, Two Electrophilic S-Linked Conjugates of Methyl hocyanate. Slattet, M.S. Rashed, D.-H. Han, and T.A. Billie. ι Identification of Epoxide- and Quinone-Derived
P.G. Pearson, J.G.
Bromobenzene Adducts to Protein Sulfur Nucleophiles. D.E.
Slaughter and R.P. Hanzlik. ι Mass Spectrometry Analysis of Tobacco-Specific Nitrosamine-DNA Adducts in Smokers and Nonsmokers. Foiles, S.A. Akerkar, S.G. Carmella, M. Kagan, G.D. Stoner, J.H. Resau, and S.S. Hecht.
P.G.