Closing the gap in membrane imaging - Analytical Chemistry (ACS

Dec 1, 2006 - Closing the gap in membrane imaging. Thomas Hayden. Anal. Chem. , 2006, 78 (23), pp 7916–7916. DOI: 10.1021/ac0694932. Publication ...
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Closing the gap in membrane imaging A novel combination of imaging techniques reveals fine-scale organization in lipid bilayers.

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the mol % concentrations of he lipid-bilayer membranes of Cs+ (a) DLPC and DSPC in the imaged cells are made up of a chemiRaster beam (b) regions. Some features, easily cally diverse assortment of phos(a) 31 – misidentified as domains by AFM, pholipids and proteins. Lateral variP 13 1 – 12 15 – CH were shown to be debris—they ations in membranes’ compositions C N 12 15 – 12 – C N C contained no isotopic label. Tiny have long been proposed to play a 12 – 12 15 – C C N (