Comparison of Cationic and Amphipathic Cell Penetrating Peptides for

Dec 15, 2011 - Comparison of Cationic and Amphipathic Cell Penetrating Peptides for siRNA Delivery and Efficacy. Robert H. Mo, Jennica L. Zaro, and We...
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Article pubs.acs.org/molecularpharmaceutics

Comparison of Cationic and Amphipathic Cell Penetrating Peptides for siRNA Delivery and Efficacy Robert H. Mo, Jennica L. Zaro, and Wei-Chiang Shen* Department of Pharmacology and Pharmaceutical Sciences, University of Southern California School of Pharmacy, Los Angeles, California 90033, United States ABSTRACT: Cell penetrating peptides (CPPs) are short strands of arginine- and/or lysine-rich peptides (