Contents
FEATURES 248 A On the Cover. MIPs as Chromatographic Stationary Phases for Molecular Recognition. Molecular imprint polymers (MIPs) can selectively recognize target molecules even in the presence of structurally and functionally similar compounds. Vincent T. Remcho and Z. Jessica Tan of Oregon State University discuss how MIPs are being used as separation media, especially for analyzing chiral compounds.
Chiral compound separator. Page 248 A.
257 A From Flow Injection to Bead Injection. Jaromir Ruzicka and Louis Scampavia of the University of Washington describe a new methodology that combines the advantages of solid-phase chemistry with the novelty of fluidic handling of microcarrier beads. Chemical reactions occur at the bead surfaces and can be analyzed in real time; then, at the end of the measurement cycle, the beads are discarded, collected, or rerouted. NEWS 239 A Analytical Currents Shrinking traps. • Vapor-sensing zeolite. • Immunoaffinity-based SPE with GC. • Entropic trapping of macromolecules. • Monitoring protein unfolding. • Characterizing large proteins. • Sequencing "trouble" spots. • Single molecules by STM. • Oligonucleotide fragmentation. • Microelectrodes for mismatch detection. • Imaging particles.
Bead injection onalysis. Page 256 A.
243 A Science The eyes have it. While most scientists design instruments with sophisticated optics and detectors, Joseph R. Lakowicz and co-workers at the University of Maryland School of Medicine have developed a generic method for fluorescence polarization sensing, which relies only on the human eye as the detector. 244 A News from HPCE ’99 Coordination ionspray MS. • Correlating enzymatic activity and cell cycle. 245 A Government and Society Copyright competition. • NIST opens new research facility. 245 A Business HP to split. 246 A People Abraham Savitzky. • Year 2000 Division of Analytical Chemistry Awards.
Multianalyte vapor sensor. Page 239 A.
'This article is also available on the Web at http://pubs.acs.org, under "Hot Articles".
224 A
Analytical Chemistry News & Features, April 1, 1999
ANALYTICAL CHEMISTRY APRIL 1, 1999/VOL. 71 NO. 7 ANCHAM 223A-288 A/1241-1484 (1999) ISSN 0003-2700
DEPARTMENTS 227 A Editorial The climbing syndrome (anthills). Many of us are accustomed to "mud slinging" among political candidates, but such conduct has no place in descriptions of scientific progress.
231 A In AC Research 264 A Focus The incredible shrinking mass spectrometers. A shoe-box-sized quadruplle mass spectrometer, the 'Tiny TOF", a 0.4-T FT-ICR, ion traps with inner radii measured in millimeters, and other miniature devices are currently being develoned. Rut what eood are thev?
Bee-small and useful. Page 264 A.
271 A Product Review GC at a standstill. Has the market for gas chromatographs peaked at $1 billion?
278 A Books and Software One-semester course on chemical analysis. Contemporary Chemical Analysis is reviewed by Michael E. Ketterer of Northern Arizona University. • Getting the complete view. A Global View ofLC/MS ii ieviewed by Lester Taylor rr MDS Panlabs. • Book received. • Software released.
280 A New Products A thermal analyzer and a gas chromatograph for routine production analyses are featured. • Instrumentation. • Literature. • Catalogs. • Columns. • Chemicals.
A look at gas chromatographs. Page 271 A.
2 8 2 A Meetings HPLC '99 meets in Granada, Spain. • Conferences. • Short courses.
286 A Information Express 1C
AC Research Contents
12411483 AC Research 1484 Author Index
Registered in U.S. Patent and Trademark Office © Copyright 1999 by the American Chemical Society
Analytical Chemistry News & Features, April 1, 1999 225 2
