Correction to “Chiral Cyclohexane 1, 3-Diones as Inhibitors of Mutant

Correction pubs.acs.org/acsmedchemlett

Correction to “Chiral Cyclohexane 1,3-Diones as Inhibitors of Mutant SOD1-Dependent Protein Aggregation for the Treatment of ALS” Yinan Zhang, Radhia Benmohamed, Wei Zhang, Jinho Kim, Christina K. Edgerly, Yaoqiu Zhu, Richard I. Morimoto, Robert J. Ferrante, Donald R. Kirsch, and Richard B. Silverman* ACS Med. Chem. Lett. 2012, 3, 584−587. DOI: 10.1021/ml3000963

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n Page S4 of the Supporting Information, the synthesis of (R)-5-(1-(3,5-bis(trifluoromethyl)phenoxy)ethyl)cyclohexane-1,3-dione (1a) indicates the starting material to be (R)-ethyl lactate, and on page S5, the synthesis of (S)-5-(1(3,5-bis(trifluoromethyl)phenoxy)ethyl)cyclohexane-1,3-dione (1b) indicates the starting material to be (S)-ethyl lactate. Both are reversed: the starting material for 1a should be (S)-ethyl lactate, and the starting material for 1b should be (R)-ethyl lactate.

© XXXX American Chemical Society

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DOI: 10.1021/acsmedchemlett.7b00070 ACS Med. Chem. Lett. XXXX, XXX, XXX−XXX