Correction to “Oxidative Substitution of Boranephosphonate Diesters

Addition/Correction pubs.acs.org/JACS

Correction to “Oxidative Substitution of Boranephosphonate Diesters as a Route to Post-synthetically Modified DNA” Sibasish Paul, Subhadeep Roy, Luca Monfregola, Shiying Shang, Richard Shoemaker, and Marvin H. Caruthers* J. Am. Chem. Soc. 2015, 137, 3253−3264. DOI: 10.1021/ja511145h S Supporting Information *

Supporting Information. In Figure S19, the LC-MS profile for ODN 15 as obtained from 37 scans has been added as part B. The ESI scans shown in parts A and B were obtained from the same sample. These ESI scans (16 and 37, respectively) generate essentially the same results. In Figure S21, the LC-MS profile for ODN 17 as obtained from 34 scans has been added as part B. The ESI scans as shown in parts A and B were obtained from the same sample. These ESI scans (78 and 37, respectively) generate essentially the same conclusions. As expected with more scans, several additional minor side products/impurities were observed with the profile from 78 scans as published. These LC-MS profiles were obtained from unpurified reaction mixtures as obtained from the controlled pore glass supports following synthesis. The quality of these products should be compared to the results obtained when the same crude reaction mixtures were analyzed by denaturing polyacrylamide gel electrophoresis (see Figure 2 in the original article). These additions do not alter any of the results or conclusions as presented in original publication.

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ASSOCIATED CONTENT

S Supporting Information *

The Supporting Information is available free of charge on the ACS Publications website at DOI: 10.1021/jacs.7b08410. Detailed synthetic procedures, characterization information, LC-MS spectra of the oligomers synthesized, and NOESY spectra (corrected: Figures S19B and S21B added) (PDF)

Published: September 15, 2017 © 2017 American Chemical Society

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DOI: 10.1021/jacs.7b08410 J. Am. Chem. Soc. 2017, 139, 13586−13586