Addition/Correction Cite This: Inorg. Chem. 2019, 58, 8893−8893
pubs.acs.org/IC
Correction to Curcumin “Drug” Stabilized in Oxidovanadium(IV)BODIPY Conjugates for Mitochondria-Targeted Photocytotoxicity Utso Bhattacharyya, Brijesh Kumar, Aditya Garai, Arnab Bhattacharyya, Arun Kumar, Samya Banerjee, Paturu Kondaiah,* and Akhil R. Chakravarty* Inorg. Chem. 2017, 56 (20), 12457−12468. DOI: 10.1021/acs.inorgchem.7b01924
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S Supporting Information *
Page 12464, right column. Line 6 (from bottom): “10 μM” corrected to “250 μM for 1a and 50 μM for others”. Line 4 (from bottom): “9, 20” corrected to “13, 24”. Lines 1 and 2 (from bottom): “42, 60, and 90%” corrected to “ ∼74, 65, and 88%”. Page 12465, left column. Line 2: “10 μM” corrected to “50 μM” and “25 μM” corrected to “250 μM”. Line 7: “94%” corrected to “91%”. Line 8: “30%” corrected to “22−30%”. Line 10: “60%” corrected to “55−65%”. Line 12: “25 μM” corrected to “250 μM”. Line 15: “85% to 20%” corrected to “81% to 55− 60%”. Line 26: “∼47% and ∼66%” corrected to “∼17% and ∼71%”. Right column. Line 10 (from bottom): “bar diagrams” corrected to “raw gel diagrams”. The extent of DNA cleavage (% NC) was determined by measuring the intensities of the bands (SC and NC forms of plasmid DNA) using a UVITECH Gel Documentation System. Page 12465, right column. Line 15: “... formation of hydroxyl radicals ...” corrected to “... formation of only hydroxyl radicals ...”. Line 17: “... displayed significant generation ...” corrected to “ ... displayed primarily generation ...”. We found errors in Figure 9. These are corrected, and the revised figure is given along with the revised caption. The data are sourced from the full-page raw gel diagrams that are given as Figures S35−S37 in the revised Supporting Information (SI).
1 h exposure time: lane 1, DNA control; lane 2, DNA + 3a; lane 3, DNA + KI + 3a; lane 4, DNA + DMSO + 3a; lane 5, DNA + catalase + 3a; lane 6, DNA + 3a + SOD; lane 7, DNA control; lane 8, DNA + 3a; lane 9, DNA + 3a + D2O; lane 10, DNA + 3a + TEMP; lane 11, DNA + 3a + NaN3. (b) Lane 2 in the dark (D) and the rest in light of 532 nm for 1 h exposure time: lane 1, DNA control; lane 2, DNA + 1a (D); lane 3, DNA + 1a; lane 4, DNA + 1a + D2O; lane 5, DNA + 1a + TEMP; lane 6, DNA + 1a + NaN3; lane 7, DNA control; lane 8, DNA + 1a; lane 9, DNA + 1a + SOD; lane 10, DNA + DMSO + 1a; lane 11, DNA + 1a + KI; lane 12, DNA + catalase + 1a [pUC19 DNA, 0.2 μg, 30 μM base pair; ligands, 2a and 3a, 50 μM; complex 1a, 250 μM; KI, NaN3, TEMP, 0.5 mmol; D2O, 16 μL; catalase and SOD, 4 units].
Figures S35−S37 in the SI are revised with full-page gel diagrams. The original DCFDA figure (Figure S26) had an error that is corrected. All of these figures are given in the revised SI file. The corrections described here in the DNA photocleavage studies and DCFDA assay do not alter or invalidate any of the conclusions reported in the original publication. These were experimental errors, and we sincerely apologize for these oversights.
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ASSOCIATED CONTENT
S Supporting Information *
The Supporting Information is available free of charge on the ACS Publications website at DOI: 10.1021/acs.inorgchem.9b00931. Details of the experimental procedures, reaction scheme, ESI-MS, IR spectra, d−d transitions of 1−3, cyclic voltammograms, UV−visible stability data, ESI-MS of complexes, crystal structure (ORTEP and unit-cell packing diagrams showing H-bonding), electronic transitions by DFT, time-dependent cellular incorporation assay, MTT assay plots, confocal images of 1a, cell cycle profiles of 1a−3a, Annexin assay profile of 3a, DCFDA assay, DPBF absorbance decay plots, DNA binding data, DNA photocleavage bar diagrams, DFT data for the complexes, a list of M−O(Cur) bond distances of structurally characterized curcumin complexes (PDF) Figure 9. (A) Lanes 1−6 in the dark (D): lane 1, DNA control; lane 2, DNA + L1; lane 3, DNA + L2; lane 4, DNA + Hcur; lane 5, DNA + 2a; lane 6, DNA + 3a. Lanes 7−13 in light of 532 nm (1 h exposure time): lane 7, DNA control; lane 8, DNA + L2; lane 9, DNA + 2a; lane 10, DNA + 3a; lane 11, DNA control; lane 12, DNA + L1; lane 13, DNA + curcumin (Hcur). (B) (a) Data in light (L) of 532 nm for © 2019 American Chemical Society
Published: June 17, 2019 8893
DOI: 10.1021/acs.inorgchem.9b00931 Inorg. Chem. 2019, 58, 8893−8893
