Addition, Retraction, Correction pubs.acs.org/acschemicalbiology
Correction to Mutasynthesis of a Potent Anticancer Sibiromycin Analogue Isaac T. Yonemoto, Wei Li, Ankush Khullar, Natàlia Reixach, and Barbara Gerratana* ACS Chem. Biol. 2012, 7, 973−977. DOI: 10.1021/cb200544u
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his correction is issued with respect to the DNA melting point assay in our original article. Specifically, on page 976 in the Methods section, we state “DNA:PBD = 1:20” was used in the DNA melting point assay, which is incorrect. The correct representation is likely “DNA:PBD = 20:1” but requires confirmation with further experimentation. Consequently, we withdraw the Tm measurements described in the second paragraph of page 974 and the conclusion that deoxysibiromycin binds more tightly to DNA than sibiromycin. Future experiments repeating the melting point assay will be admitted into the scientific record. This correction does not change any other aspects in the interpretation of data, analysis, or the article’s conclusions. The authors apologize for this unintended error.
Published: April 15, 2014 © 2014 American Chemical Society
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dx.doi.org/10.1021/cb5002476 | ACS Chem. Biol. 2014, 9, 1214−1214
