Correction to Total Synthesis of (−)-Histrionicotoxin - Organic Letters

Addition/Correction pubs.acs.org/OrgLett

Correction to Total Synthesis of (−)-Histrionicotoxin Yohei Adachi, Noriyuki Kamei, Satoshi Yokoshima, and Tohru Fukuyama* Org. Lett. 2011, 13(16), 4466−4449. DOI: 10.1021/ol2018032 S Supporting Information *

S

olvent peaks had been removed from the 1H NMR spectra reported for compounds 8, 12, S3, and S10. Peaks of impurities had been removed from the 1H NMR spectra reported for compounds 6 and S18. Original FIDs were located, and the spectra were reprocessed and have been replaced for the above compounds in the revised Supporting Information submitted with this correction. The spectra editing did not affect any of the conclusions of the published paper. The purities calculated on the basis of the revised spectra and corrected yields are as follows: 8 (95% purity, 91% yield), 12 (95% purity, 92% yield), S3 (97% purity, 88% yield), and S10 (96% purity, 86% yield). Impurities included in 6 were tri-nbutylphosphine and ethanol, and the purity and the yield were calculated as 58% purity and 50% yield on the basis of the revised spectrum. The sample of S18 included some unknown impurities; thus, the exact purity could not be determined.

■

ASSOCIATED CONTENT

* Supporting Information S

Revised Supporting Information including reprocessed spectra. This material is available free of charge via the Internet at http://pubs.acs.org.

Published: February 3, 2014 © 2014 American Chemical Society

1273

dx.doi.org/10.1021/ol5001632 | Org. Lett. 2014, 16, 1273−1273