Correction to Understanding Enzyme Inhibition

Chemical Education Today

Correction An error appears in my article, Understanding Enzyme Inhibition (Ochs, R. S. J. Chem. Educ. 2000, 77, 1453– 1456). The description of the lower curve in Figure 2 is labelled as “noncompetitive”. Instead it should be labeled as “uncompetitive”. It is correctly given in the legend. Raymond S. Ochs Department of Pharmaceutical Sciences St. John’s University, Jamaica, NY 11439 [email protected]

Figure 2. Uncompetitive inhibition. In the direct plot (v i vs [S]) inhibition is maximal at high [S] (the Vmax asymptote of the control) and diminishes to zero as [S] approaches zero (the Vmax/ Km tangent line of the control).

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Journal of Chemical Education • Vol. 78 No. 1 January 2001 • JChemEd.chem.wisc.edu