Addition/Correction pubs.acs.org/joc
Corrections to “Pyridinium Boranephosphonate Modified DNA Oligonucleotides” Subhadeep Roy, Sibasish Paul, Mithun Roy, Rajen Kundu, Luca Monfregola, and Marvin H. Caruthers* J. Org. Chem. 2017, 82 (3), 1420−1427. DOI: 10.1021/acs.joc.6b02599 S Supporting Information *
Page 1425: Compound 2 should be named 3′-O-1,1dimethylcyanoethylborane-d3-phosphonate-5′-O-dimethoxytrityl-2′-deoxythymidine instead of 3′-O-bis(1,1-dimethylcyanoethyl)borane-d3-phosphonate-5′-O-dimethoxytrityl-2′-deoxythymidine. Page 1426: We note the change in the time of oxidation compared to the previously reported method. It should read as follows: Solid-Phase Pyridinium Boranephosphonate DNA Synthesis. ODNs containing boranephosphonate linkages were synthesized as described previously4 on a 0.2 μmol scale on a highly cross-linked polystyrene resin using 5′-dimethoxytrityl2′-deoxythymidine-3′-O-cyanoethyl-N,N-diisopropylphosphoramidite. The only change made to the previously reported method was to increase the oxidation time with peroxide at positions that contained a phosphate linkage to 60 s.
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ASSOCIATED CONTENT
* Supporting Information S
The Supporting Information is available free of charge on the ACS Publications website at DOI: 10.1021/acs.joc.7b01022. In Figures S5, S8, and S11, the solvent peak in each of these 1H NMR spectra has been labeled (PDF)
© XXXX American Chemical Society
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DOI: 10.1021/acs.joc.7b01022 J. Org. Chem. XXXX, XXX, XXX−XXX
