CRYSTALLOGRAPHIC D A T A
123. Aricine
Crystals of ssieine suitable for crystallographic work may be obtained by recrystdlii;ing from methanol solution. The x-ray powder diffraction data were obtained using a camera 114.6 mm. in diameter with chromium radiation and vanadium filter. A wave-length vduc of 2.2896 A. was used in the calculations.
HARRY A. ROSE and ANN VAN CAMP, Lilly Research Laboratoriw, Indianapolis 6, Ind.
CRYSTAL MonrnoLoaY Crystal System. Orthorhombic. Form and Habit. Blitdes elonpated parallel to e arid showing the prism [ 110). Unfortunstoly, no wy&ls were available with both ends of the bl+dep?mp!ete; hqye"z, the blades appear to be
hCH8
H,COOC-\,
:rueturd Formula for Aricine
is another alkaloid in the group of compounds which from plants of the Rauwolfia species. An account of the extraction of this alkaloid from the plant has been given by Goutarel and coworkers ( 1 ), while a discussion of the chemistry has been given by Stoll and his coworkers (SI. RICINE
A may be extracted
d.
1 -
I
. Axiiti I V ~ L L U .a,".L = U . U U ~ O I.U.UWU_ 11U A 1 I U = W'X'. Interfacial Angles (Polar, X-Kay). -
I
111 = 86"16'.
~
,graphic arieine
projection
X-RAYDIFFRACTION DILTA 14.16 A,, bo = 14.70 A,, eo = 'J 27 Coll Dimensions. a. = .. Formula Weights per tiell. 4. Formula M'eight. 382.4. Density. 1,301 grams per OD. (Hatation), 1.318 grams per cc. (a-rq
of
I
X-Ray Powder Diffraction Data d
I .~ /h
hkl
d. Calod.
10.23 7.79 7.39 6.88 6.59 6.39 5.61 5.26 5.10 4.63 4.40 4.22 4.03 z3.92 3.76 3.40 3.32 3.28 3.08 3.02 2.96 2.78 2.41 2.38 2.28 2.18
0.53 0.03 0.13 0.13 0.33
110 011,101 020 111 120 210 201 211 220
10.20 7.84.7.76 7.35 6.86 G.52
0.13 0.13 0.03 0.53 0.33 0.27
1.00 0.07 0.13
0.07 0.07 0.03
0.07 0.03
0.07 0.07 0.13 0.03 0.03 0 07 0 07
130
012,101 112 230 202 212 410,330 141 240 241 421 113 341
111A
'AL PROPERTIES
'isctivc Indices (5893 A,, 25' C.). OL = 1.525, B = 1.694, 1.710 ( y calculated from a,0,and 2V). OP'tic Axid Angle. 2V = ( - ) 30.5" (calculated from 9, and Mall8.rd's constant), 2E = (-) 53'. Optio Axial P!ane. 010. Acute Biwctnr. a = c. Dispersion. r > u. FUSION BEHAVIOR.On heating, arieinc mt!Its in the range 185-88' C. with decomposition. The melt does not crystalliee on cooling
6.38 p 63
2.26 5.10 4.62 4.42.4.41 4.22 4.02 3.89 3.78 3.44.8.40 3.32 3.28 3.08 3.03 2.96 2.80
ACKNOWLEDGMENT
The author wishes to thank Norbert Neuss of these labore, tories for supplying the crystals from which these data were obtained. The material was identical with an authentic sample of aricine kindly supplied by M. M. Janot. LITERATURE CITED
(1) Goutarel. 11.. others. Helv. Chim. Acta 37, 1805 (1954) (2) Stoll, A,, others. Ibid.. 38, 270 (1955).
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