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Cite This: ACS Appl. Mater. Interfaces XXXX, XXX, XXX−XXX
CuO Nanoparticles-Containing Highly Transparent and Superhydrophobic Coatings with Extremely Low Bacterial Adhesion and Excellent Bactericidal Property Tingting Ren,†,‡ Mingqing Yang,† Kaikai Wang,†,‡ Yue Zhang,† and Junhui He*,† †
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Functional Nanomaterials Laboratory, Center for Micro/Nanomaterials and Technology and Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Zhongguancundonglu 29, Haidianqu, Beijing 100190, China ‡ University of Chinese Academy of Sciences, Beijing 100049, China S Supporting Information *
ABSTRACT: Human health and industrial instruments have been suffering from bacterial colonization on the surface of materials for a long time. Recently, antibacterial coatings are regarded as the new strategy to resist bacterial pathogens. In this work, novel highly transparent and superhydrophobic coatings with extremely low bacterial adhesion and bactericidal performance were prepared by spray-coating hydrophobic silica sol and CuO nanoparticles. The coated glass showed high transmittance in 300−2500 nm with a maximum value of 96.6%. Compared with bare glass, its superhydrophobic characteristics resulted in a reduction in adhesion of bacteria (Escherichia coli, E. coli) by up to 3.2 log cells/cm2. Additionally, the live/dead staining test indicated that the as-prepared coating exhibited excellent bactericidal performance against E. coli. Moreover, the as-prepared coating could maintain their superhydrophobicity after the sand impact test. The proposed method to fabricate such coatings could be applied on various substrates. Therefore, this novel hybrid surface with the abilities to reduce bacterial adhesion and kill attached bacteria make it a promising candidate for biosensors, microfluidics, bio-optical devices, household facilities, lab-on-chips, and touchscreen devices. KEYWORDS: CuO nanoparticles, superhydrophobic, bacterial antiadhesion, bactericidal, high transparency
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INTRODUCTION The associated risks of bacterial adhesion and contamination on the surface of materials or further induced by infections have always had adverse effects on human health and medical processes.1−4 For example, in the hospital, there are numbers of potentially infectious objects, such as medical instruments, monitoring/anesthesia equipment, surgical tables, and ventilators. These contaminated surfaces would significantly facilitate the propagation of pathogens, leading to widespread transmission of healthcare related infections. Therefore, antibacterial coatings have become research hotspots because of the urgent requirement for developing alternatives in replacement of traditional antibiotics.1 The bacteria adhesion on surface is considered as the first process during bacterial colonization. Thus, researchers fabricated antiadhesive surfaces to eliminate bacterial adhesion, such as superhydrophobic surfaces with high water contact angle (WCA, >150°) and low rolling angle (RA,
