7584
J. Am. Chem. SOC.1980, 102, 7584-7585
Scheme I M E - CJ 7
10
&CO*Bu
1
1.L-Selectride: p - T s O H , A.65 -75%
O?i+
2 . Mel,Ag20,93%
HMP, 72%
9 -
1 . LDA,MeSS02Me,93%
OR
n
?Me
1. AcOH, 98%
2. D i b a l - H , 80%
?Me
2 . L i O H , 80% L
L
3 . TMScHC02Et, 73 %
,$+,,gi+
R=C02Bu
15 16
OH
R-CHO
17 R=Et -
tz R = H
R=-C02Et
1. ClCOSPyr, Et, N ;
TMSCI,Na1,60-70%
A,70% ( 1 : l )
,
