Monograph pubs.acs.org/doi/book/10.1021/acsreagents
d-Glucose, Anhydrous (Dextrose, Anhydrous) Part 4, Monographs for Reagent Chemicals: General Descriptions, Specifications, and Tests eISBN: 9780841230460 Tom Tyner Chair, ACS Committee on Analytical Reagents James Francis Secretary, ACS Committee on Analytical Reagents
ABSTRACT This monograph for d-Glucose, Anhydrous provides, in addition to common physical constants, a general description including typical appearance, applications, change in state (approximate), and aqueous solubility. The monograph also details the following specifications and corresponding tests for verifying that a substance meets ACS Reagent Grade specifications including: Specific Rotation, Insoluble Matter, Loss on Drying, Residue after Ignition, Titrable Acid, Chloride, Sulfate and Sulfite, Starch, Heavy Metals, and Iron.
CH2OH(CHOH)4CHO
Formula Wt 180.16
CAS No. 50-99-7
GENERAL DESCRIPTION Typical appearance . . . . . . . . Applications . . . . . . . . . . . . . Change in state (approximate) . Aqueous solubility . . . . . . . . .
. . . .
. . . .
. . . .
. . . .
. . . .
. . . .
. . . .
. . . .
. . . .
. . . .
. . . .
white solid analytical standard melting point, 146 °C 91 g in 100 mL at 25 °C
SPECIFICATIONS Specific rotation [α]25°D . . . . . . . . . . . . . . . . +52.5° to +53.0°
© 2017 American Chemical Society
A
DOI:10.1021/acsreagents.4153 ACS Reagent Chemicals, Part 4
ACS Reagent Chemicals
Monograph
pubs.acs.org/doi/book/10.1021/acsreagents
Insoluble matter . . . . . . . Loss on drying . . . . . . . . Residue after ignition. . . . Titrable acid . . . . . . . . . Chloride (Cl) . . . . . . . . . Sulfate and sulfite (as SO4) Starch . . . . . . . . . . . . . Heavy metals (as Pb) . . . . Iron (Fe) . . . . . . . . . . . .
. . . . . . . . .
. . . . . . . . .
. . . . . . . . .
. . . . . . . . .
. . . . . . . . .
. . . . . . . . .
. . . . . . . . .
. . . . . . . . .
. . . . . . . . .
. . . . . . . . .
. . . . . . . . .
. . . . . . . . .
. . . . . . . . .
. . . . . . . . .
Maximum Allowable 0.005% 0.2% 0.02% 0.002 meq/g 0.01% 0.005% Passes test 5 ppm 5 ppm
TESTS Specific Rotation [Part 2: Measurement of Physical Properties; Specific Rotation]. Weigh accurately about 10 g, and dissolve in 90 mL of water in a 100 mL volumetric flask. Add 0.2 mL of ammonium hydroxide, and dilute with water to volume at 25 °C. Observe the optical rotation in a polarimeter at 25 °C using sodium light, and calculate the specific rotation. It should not be less than +52.5° nor more than +53.0°.
Insoluble Matter [Part 2: Gravimetric Methods; Insoluble Matter]. Use 20 g dissolved in 150 mL of water.
Loss on Drying Weigh accurately about 1 g, and dry in a preconditioned weighing bottle at 105 °C for 6 h.
Residue after Ignition [Part 2: Gravimetric Methods; Residue after Ignition]. In a preconditioned dish, ignite 5.0 g until charred. Moisten the char with 2 mL of sulfuric acid.
Titrable Acid To 100 mL of carbon dioxide-free water, add 0.15 mL of phenolphthalein indicator solution and 0.02 N sodium hydroxide until a pink color is produced. Dissolve 10.0 g of the sample in this solution, and titrate with 0.01 N sodium hydroxide to the same end point. Not more than 2.5 mL should be required.
Chloride [Part 2: Colorimetry and Turbidimetry; Chloride]. Dissolve 0.50 g in 50 mL of water, and use 10 mL of this solution.
Sulfate and Sulfite [Part 2: Colorimetry and Turbidimetry; Sulfate; Procedure for Sulfate, Method 1]. After sample dissolution, add 1 mL of bromine water, and boil.
© 2017 American Chemical Society
B
DOI:10.1021/acsreagents.4153 ACS Reagent Chemicals, Part 4
ACS Reagent Chemicals
Monograph
pubs.acs.org/doi/book/10.1021/acsreagents
Starch Dissolve 1.0 g in 10 mL of water and add 0.05 mL of 0.1 N iodine solution. No blue color should appear.
Heavy Metals [Part 2: Colorimetry and Turbidimetry; Heavy Metals (as Lead); Procedure for Heavy Metals, Method 1]. Dissolve 6.0 g in about 20 mL of water, and dilute with water to 30 mL. Use 25 mL to prepare the sample solution, and use the remaining 5.0 mL to prepare the control solution.
Iron [Part 2: Colorimetry and Turbidimetry; Iron; Procedure for Iron, Method 1 (Ammonium Thiocyanate)]. Use 2.0 g.
© 2017 American Chemical Society
C
DOI:10.1021/acsreagents.4153 ACS Reagent Chemicals, Part 4
