Detection and Quantification of DNA Adsorbed on Solid Surfaces by

Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore 117576, Singapore. Langmuir , ...
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Detection and Quantification of DNA Adsorbed on Solid Surfaces by Using Liquid Crystals Chih-Hsin Chen and Kun-Lin Yang* Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore 117576, Singapore Received September 6, 2009. Revised Manuscript Received November 13, 2009 Conventional DNA detection is often accomplished by using UV-vis or fluorescence spectrometry, which requires at least 1 μL of DNA solution. Herein, we report a label-free, liquid-crystal (LC)-based DNA quantification method that is suitable for characterizing DNA solution volumes of