Development of Intramolecular [4+1] Cycloadditions

Page 1. Development of Intramolecular [4+1] Cycloadditions Tristan H. Lambert, Department of Chemistry, Columbia University O CO2Me H O ...
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Development of Intramolecular [4+1] Cycloadditions Tristan H. Lambert, Department of Chemistry, Columbia University

O

O CO2Me

I2, Mg(ClO4)2

CO2Me

Et3N

84% yield one-pot formal [4+1] cycloaddition QuickTime™ and a decompressor are needed to see this picture.

H O I2

CO2Me

H

MgI2 (formed in situ)