Jul 14, 2016 - polymer conjugates could enter the tumor cell cytoplasm by a nonendocytic ... KEYWORDS: nuclear drug delivery, cytoplasmic delivery, ...
Jul 14, 2016 - As the hearts of tumor cells, the nucleus is the ultimate target of many chemotherapeutic agents and genes. However, nuclear drug delivery is always hampered by multiple intracellular obstacles, such as low efficiency of lysosome escap
Jun 1, 2009 - RNA interference (RNAi) is one of the most dramatic findings over the past ... DNA-based (plasmid or viral vector) short hairpin RNA. (shRNA).
Jun 1, 2009 - RNA interference (RNAi) is one of the most dramatic findings over the past ... DNA-based (plasmid or viral vector) short hairpin RNA. (shRNA).
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Jun 21, 2017 - Antisense oligonucleotides (ODNs) are therapeutic molecules that hybridize to complementary target mRNA sequences. To further overcome ...
To further overcome the poor cellular uptake of ODNs, we proposed a novel strategy to deliver ODNs by conjugating the anti-influenza A virus (IAV) ODN with a ...
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Aug 26, 1993 - Romke Bron,* * Antonio Ortiz,$ and Jan Wilschut*. Department of Physiological Chemistry, University of Groningen, Bloemsingel 10, 9712 KZ ...
Jul 14, 2016 - Direct Cytoplasmic Delivery and Nuclear Targeting Delivery of. HPMA-MT Conjugates in a Microtubules Dependent Fashion. Jiaju Zhong,. â .
