rather awkward approach. For instance, a section on Lipids covered every aspect of lipids and membranes-structure. catabolism, anabolism, membrane functions, ete. Then the text moved on to the next macromolecule. The second edition uses a more standard topic outline. Part I (The Major Components of the Cell) discusses the structure and functions of biological macromolecules-proteins, lipids, carbohydrates, and nucleic acids. Part I1 (Catalysis) deals with enzymes and coenzymes. Part I11 (Catabolism) begins with a review of thermodynamics and an introduction to biogenergetics, then coven the energy yielding processes, including photosynthesis. The next three Parts of the teat cover Anabolism (IV), Nuel& Acid and Protein Metabolism (V), and Memhrane-Associated Reactions (VI). In his Preface, Zubay states that the text was redesigned in this manner to accommodate one term biochemistrv courses (which usually cover the first three parts, without hsving to jump from front to hack, lwing rontinuity, as in the first edition. There are many pluses to this text. As I mentioned above, the multi-author approach really does work, and the material is current. The figures are generally good, and include many of the excellent figures of Irving Geis. Some subjects are lightly covered in the text and refer to figures for a more complete understanding. In other words, students would be well advised to treat the figures as integral to the text. This seems an economical and pedagogically sound approach. The section on Catalysis discusses a number of enzyme mechanisms in addition t o the "Big Three" (lyzozyme, carboxypeptidase A, chymotrypsin). I was especially pleased with the chapter on coenzymes. Many bwks list the vitamins and eoenzymes a t this point, and then deal in a cursory manner with mechanisms in the appropriate section in metabolism. This chapter covers in a sophisticated and thorough manner the role and the mechanism of action of these coenzymes in key enzymatic processes. Chapters on metabolism then deal with metabolism, not enzyme mechanisms. Some of the pluses of this text also contribute to its minuses. This book is not for the faint of heart. I t is an advanced book and prohahly best serves senior biochemistry majors or graduate students. The use of organic and some physical chemistry and modern biology (including genetics far Part V) make it an upper level text. An Introduction gives a brief outline of chemical and biological principles needed for the text, but one assumes students have had two years of chemistry already. One cannot make that assumption regarding a student's biology background, and this introduction may be insufficient preparation for what is ahead in the text. Even though the book is thorough, this also means that it can he encyclopedic a t times. There is only so much hiochemistry that can he covered in a one-year course. If one were to conscientiously cover Parts IV, only about two lectures could he dedicated to each chapter. For a first course in biochemistry, this text could be intimidating for many undergraduates. This problem is also apparent in many of
A104
Journal of Chemical Education
Advanced lnorganlc Chemistry, Fifth Edltlon F. Albert Cotton and Geoffrey Wilklnson. 1455 Wiley: New Yo*, NY, 1988. xvii pp. Figs. and tables. 17.2 X 24.2 cm. $44.95.
book through five editions over 25 years has kept pace with the rapid maturation of inorganic chemistry. Thus, the single volume format has been maintained with the addition of considerable new material only by elimination of much of the theoretical material included in previous editions. For erample, ligand field theory and simple ideas ahout bonding are not discussed. The authors assume, quite correctly, that the student will have been exposed to the theoretical background necessary to understand modern descriptive inorganic chemistry in lower level texts. With this in mind, the authors extensively use arguments based on molecular orbital theory to rationalize experimental results throughout the hook. In addition to the new material added, several sections and many chapters have been rearranged and reworked. Part One, Survey of Principles, contains two brief chapters: Concepts of Stereochemistry and Bonding and Introduction to Ligands and Complexes. The previous format is retained with 14 chapters on the Chemistry of The Main Group Elements in Part Two: Hydrogen; Group M I ) ; Group IIA(2); Boron; Group IIIA(13); Carbon; Group IVA(14); Nitrogen; Group VA(15); Oxygen; Group VIA(16); Group VIIA(17);Group VIIIA(18); Group IIB(12) and with 5 chapters on The Chemistry of the Transition Elements in Part Three: Survey of the Transition Elements; First Transition Series; Second and Third Transition Series; The Lanthanides, also Scandium (IIIB,3) a n d Yttrium (IIIB,3); Actinium, Thorium, Protactinium and the Actinide Elements. Part Four has been extensively augmented, especially the eight chapters devoted to various aspects of organometallic chemistry of the transition metali: Transition Metal Carbon Monoxide Compounds; Metal-ta-Metal Bonds and Metal-Atom Clusters; Transition Metal Compounds with Bonds to Hydrogen; Compounds with Transition Metal Single, Double, and Triple Bonds to Carbon; Compounds of Transition Metals with Alkenes and Delocalized Hydrocarbon Systems; Oxidative-Addition and Migration (Insertion) Reactions; Homogeneous Catalytic Synthesis of Organic Chemicals hy Transition Metal Complexes. Chapters on Reaction Meehanisms of Transition Metal Complexes and Bioinoraanic Chemistry complete Part . Four. The general format of the b w k is similar ta the fourth edition in that it contains no exercises or study problems. The specific and additional references are current, mostlyfrom mid-1979 to mid-1987. Older work is only referenced in previous editions. The appendices have been revised with deletion of sections from the fourth edition on atomic orbitals, quantum states and magnetic properties and with addition of sections on ionic radii and molecular svmmetrv (moved . from the h d y uf the text in previou~editrons). Happily, the index ha3 been expande d s i ~ i f i c a n t l yfrom 30tu45pages. Anuther improvement in the hook is the typography; on the stark white paper the type is dark, clear, and easy to read.
Reviews of the previous four editions of this classic comprehensive text on inorganic chemistry have appeared in this Journal 1963,40,230; 1967,44, A240; 1973,50, A347; 1981, 58, A204. The development of the
(Continued on page A106)
the Selected Readines listed a t the end of each chanter. Some &soter references are u, sperralmd monographs or serlrs that may not be found at many four-year under graduate colleges. Some references are not very specific;for instance, to all 131volumes of Methods in Enzymology. Of course, this is an impartant series that students should know about, but they would benefit more from specific Scientific American or Annua l Reuiews of Biochemistry articles. Some authors do list references from these more readily available sources. In summary, this is s h w k that no hiachemist or biochemistry teacher should be without. For biochemistry majors with a strong chemistry and biology background, or graduate students, it is certainly one of the best texts on the market. But I would think twice before using it in a first course in biochemistry with a varied audience. Charles L. Bering Clarion Unlverslty of Pennsylvania Clarion, PA 16214
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rganlc Chemistry, Second Edltion G. Marc Loudon. BenjaminlCummings: Menlo Park, CA, 1988. 1259 pp. Figs. and tables. 20.8 X 26 cm.
In this text the selection and organization of subject matter places organic chemistry most naturally in (the whole of) science subject matter. Use is made of information learned in chemistry prerequisite. Through the employment of clear, concise, and accepted mechanisms G. Mare Loudou's Organic Chemistry (second edition) presents subject matter in a moat understandable manner, while a t the same time it provides a framework for users (professors and students) to include new information as it becomes available from experimentation. Explanations are improved by excellent diagrams and pictures. Data and examples necessary for problem-solving experience abound. A large number of problems of different levels of difficulty are included. I believe the text itself would have been improved had answers to some of the prohlems been included in it. Indices and appendices are well done with many clarifying features. No explanation of the cover diagram can he easily found within the text. S. Miles Wood Rmevelt University Chicago. IL 60605
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ization; activation of small molecules: clusters and the metal-metal hond; applications to organic synthesis; oxidation and high-oxidation-state complexes; and hioorgsnometallie chemistry. The volume is thoroughly up to date in all aspects, and in nomenclature it employs that dernier cri-the new IUPAC group designation for the elements in addition to the familiar Mendeleev group numbers. The author is to he commended for his inclusion of history, hut in doing so, he has inadvertently introduced s number of errors in dates: Werner's coordination theory was published in 1893, not 1896 (p. 3), and he received the Nohel Prize in 1913, not 1915 (p. 5); Frankland's attempt to prepare free ethyl radicals dates from 1848, not 1857 (p. 38); Grignard first prepared organomagnesium halides in 1900, not 1903; and Zeise first prepared the salt that hears his name in 1827, not 1837 (p. 89). Fischer is spelled correctlv throuehout the text hut is misspelled in the Index. These few minor errors notwithstandmg, this excellent testbwk should find wide use by students and researchen alike. George B. Kauffman California State University. Fresno Fresno. CA 93740
Although the length of the hook has increased only modestly (59 pages to give a total of 1455 pages), the heft of the hook is rapidly approaching the "pumping iron" stage (2.09 kg Fourth Edition to 2.45 kg Fifth Edition). This inconvenience, however, is trivial since once again the authors have, quite admirably, achieved the purpose of the hook: "To provide the student with the background necessary to comprehend current literature in inorganic and certain aspects of organometallic chemistry." Every student with a serious interest in inorganic chemistry should have the fifth edition. Laurence J . Boucher Arkansas Stste University State University, AR 72467
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Chemistry ol t h e ransition Metals Robert H Crabtree. Wiley: New York, NY, 1988. xv 422 pp. Figs. and tables. 15 X 22.7 cm. $39.95.
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Theo~sn~~metaUicch~miatryofthe transition metal. bas played a prominent role in the renaissance in inorganic chemistry that began in the 1950s. This intense research activity has resulted not only in the discovery of many new compounds but also in the elucidation of their structures and in the a~nlieationof their unusual nronerties to the solution of practical problems. The field is a young and vigorous one, and muchof the research described in the hook under review has been carried out during the last 15years (references as late as 1987, the year of the completion of the manuscript, are included). In an era of increasingly lengthy texthooks the appearance of this concise hut authoritative volume, intended for senior undergraduate or graduate courses in organometallic chemistry or research workers in related fields desiring a better acquaintance with the suhjeet, is most welcome. Based on a course given by the author for a numher of years at Yale University, the hook consists of 16 self-contained chaders (each provided with an extensive list df references and thought-provoking problemswith solutions (10 pp.) a t the back of the hook), a three-page List of abbreviations, and a six-page index. Replete with structural formulas, equations, renctron schemes, figures, and tables, it deals lucidly with the most important topics m the field, including general bropertiei and characterization of organometallic compounds; metal-earbon and metal-hydrogen honds; ligand suhstitution reactions; complexes of pi-bound ligands; oxidative addition and reductive elimination; insertion and elimination; nueleophilie and electrophilic addition and abstraction; homogeneous catalysis (one of the most significant applications of organometellic chemistry and an important factor in the rapid development of the field as a whole); earhenes, metathesis, and polymer-
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A106
J J Handbook of Hazardous Waste
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Journal
of Chemical Education
Management for Small Quantity Generators Russell W. PhMer and Wllllam R. McTigue, Jr. Lewis Publishers: Chelsea. MI. 1988. xv 198 pp. Figs. and tables. 15.8 X 23.5 cm. $39.95.
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Public demand for the orotection of our enwronment forced Cmgress to l e p l a t e rulesgovernmg the handlmg end drapuval of toxic wastes a t a rate which has tended to exceed the ability of generators to comply. Targets have now moved from large businesses to small quantity generators (as specifically defined). Colleges and high schools, too, may now find that their practices in waste handling are subject to control by federal or state regulations, hut there still is substantial confusion about what is covered, what to do, and where to take regulated materials. This is an essential source hook for administrations uncertain about the status of their institutions. and it will he a helpful quick ref. . erence for responsible persons in schools with operating departments at work on complisnee. It will heuseful to teachers who are training scientists and engineers for life in the real world. The applicable federal laws, lists of regulated materials, proper handling, ultimate disposal, and liabilities for noncompliance all are collected in this small book. There are addresses and telephone numbers of regional EPA offices and of state aeencies. The opening chapter has the title "Why Yuu Need This Bwk". This reviewer thinks that eduraturs willappreciate the well-organized reasons why. Malcolm M. Renfrew University of Idaho MOSCOW. ID 83843
