Amino Acids. IV. Amino Acids Related to Serine - Journal of the

John H. Billman, and Earl E. Parker. J. Am. Chem. Soc. , 1945, 67 (7), pp 1069–1070. DOI: 10.1021/ja01223a011. Publication Date: July 1945. ACS Lega...
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AMINOACIDSRELATED TO SERINE

July, 1945

not all of these unreactive groups can be liberated in the presence of urea. When both heat and urea are used as denaturing agents, all tyrosine groups become available for iodination. (4)

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From the kinetic data, a computation has been made of the number of free tyrosine groups in pepsin and in serum albumin. BERKELEY, CALIFORNIA RECEIVED FEBRUARY 12, 1945

[CONTRIBUTION OF THE CHEMICAL LABORATORY OF INDIANA UNIVERSITY ]

Amino Acids.

IV. Amino Acids Related to Serine

BY JOHN H. BILLMAN AND EARLE. PARKER A new method' for synthesizing amino acids has now been extended to include the conversion of d.ihydric and trihydric amino alcohols to 8-hydroxy-a-amino acids. The amino alcohols were first allowed to react with benzoic acid in xylene to yield the corresponding oxazolines (I).

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