News Analytical Chemistry Division Names Award Winners The Fellowship Committee of the American Chemical Society Division of Analytical Chemistry has announced the winners of two $5,000 full-year awards for 1976 and five $1,000 summer fellowships. Winners of the full-year awards are Linda Upton of Seton Hall University and David Baxter of Michigan State University. Linda Upton, whose award is sponsored by the Perkin-Elmer Corp., is working with L. J. Cline Love. She is interested in obtaining the physical parameters that reflect effects of electronic molecular structure, such as singlet state lifetimes, quantum yield, and spectral information, on licit drugs and their metabolites. David Baxter's major research is being performed with Stanley R. Crouch and involves the automated determination of concentration profiles of free atoms above an electrically heated filament atomizer. The system is computer controlled and allows mapping the free atom concentration as a function of two-dimensional position of the atomizer. Procter & Gamble is the sponsor of this award. The recipients of the $1,000 summer fellowships are: Glenn D. Boutilier, University of Florida; John D. Fassett, Cornell University; Ronald E. Shoup, Purdue University; Larry F. Whiting, University of Georgia; and Richard J. Winslow, University of Massachusetts. Glenn D. Boutilier, whose award is sponsored by the Society for Analytical Chemists of Pittsburgh, is involved with J. D. Winefordner on research work which includes the construction of a pulsed source-time resolved phosphorimeter and its evaluation for analytical utility. This will include studies of signal-to-noise ratios, sensitivity, selectivity, use of inorganic probes,
Glenn
Boutilier
John
Fassett
Linda Upton
David Baxter
Ronald
Shoup
and structure-lifetime correlations in different solvents. John D. Fassett, in collaboration with George H. Morrison, has developed a system for point-by-point digitization of ion micrographs for eventual quantitation of ion images. He will be using the system to evaluate the effect of various parameters of the technique of secondary ion mass spectrometry on the illumination of photographic detection. His fellowship is sponsored by the Division of Analytical Chemistry, Dozart Fund. Ronald E. Shoup, sponsored by the Division of Analytical Chemistry and working with Peter T. Kissinger, is principally involved with hydrodynamic thin-layer electrochemistry, both for kinetic and analytical purposes. He has worked extensively with biological fluids and biochemical redox reactions. Larry F. Whiting, working with Peter W. Carr, is being sponsored by the Division of Analytical Chemistry. He will be working on the DSC modification as applied to enzyme-substrate characterization. He will develop a working error guideline for kinetics in DSC by using the orthogonal collocation method of simulation. Richard J. Winslow is working in the area of mass spectroscopy with Ramon M. Barnes. The objective of his research is to determine the operating parameters necessary for the optimum generation of specific reactive forms, i.e., positive and negative oxygen ions, within a low-pressure radio frequency oxygen plasma. This will possibly allow a specific ion to be extracted from the plasma and used as a charge exchange reagent for a mass spectrometer ionization source. This award is being sponsored by Olin Corp. Charitable Trust.
Larry
Whiting
Richard
Winslow
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News matter. The award was presented to Dr. Karle in ceremonies held at NRL, June 14.
University of Colorado Professor Awarded Harold F. Walton, professor of chemistry at the University of Colora do, Boulder, has been awarded the Medallion of the Colorado Section of the American Chemical Society at the section's April meeting held at the Marathon Oil Co. Research Center in Littleton. The award recognizes Dr. Walton's numerous contributions to the field of ion exchange and chroma tography. Dr. Walton's award address, entitled "The Place of Ion Exchange Resins in Modern Liquid Chromatog raphy", summarized his recent studies
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Harold F. Walton on ion exchange, ligand exchange, and liquid chromatography and their im plications for chemical analysis. Pro fessor Walton, a native of England, re ceived a BS and PhD from Oxford University. After a postdoctoral fel lowship at Princeton and a brief stint in industrial research, he joined the faculty of Northwestern University where he taught until 1947. He has been at the University of Colorado since. Professor Walton served on the Advisory Board of ANALYTICAL C H E M I S T R Y from 1972-74 and au thored the "Ion Exchange and Liquid Column Chromatography" review ar ticle in 1976 Fundamental Reviews.
Canadian Chemist Wins CIC Award
V. K. Rowe professional associations related to toxicology and industrial hygiene, in cluding the American Chemical Soci ety. A graduate of Cornell College (Iowa) in 1946 with an AB degree in chemistry and biology, Dr. Rowe later earned an MS degree in biochemistry and bacteriology from the University of Iowa. He received an honorary doc torate of science degree from Cornell College in 1971.
NRL Scientist Honored Twice in Week Jerome Karle, chief scientist of the Laboratory for Structure of Matter at the Naval Research Laboratory, has been elected a member of the National Academy of Sciences and also was named recipient of the 1976 Captain Robert Dexter Conrad Award for Sci entific Achievement, both within one week. The award, established within the Navy Awards Program in 1957 in
Israel
Hoffman
and a $500 honorarium from Fisher Scientific Co., was presented to Dr. Hoffman during the 59th Canadian Chemical Conference and Exhibition in London, Ontario, June 6-9. Many of Dr. Hoffman's analytical methods relating to problems of agricultural in terest enjoy international acceptance and are widely used throughout the world. He has authored more than 80 research papers. His works on arsenic and selenium residues in agricultural products are now considered classics.
Eleventh International Symposium on Advances in Chromatography
Dow Chemical Scientist Honored For his outstanding contribution to the field of toxicology and industrial hygiene research, V. K. Rowe of The Dow Chemical Co. received the Merit Award of the Society of Toxicologists. The award was presented to Dr. Rowe at the society's 11th annual meeting in Atlanta, March 18. Dr. Rowe is a past president of the American Academy of Industrial Hygiene, a member of the American Board of Industrial Hy giene, and a charter member and past president of the Society of Toxicolo gists. He is also a member of many
In recognition of his distinguished contributions in analytical chemistry, Israel Hoffman, Executive Secretary of the National Research Council's As sociate Committee on Scientific Crite ria for Environmental Quality, Otta wa, was named winner of the Fisher Scientific Lecture Award for 1976 by the Chemical Institute of Canada. The award, consisting of a framed scroll
Jerome Karle memory of the late Captain Conrad's contribution to Navy science, recog nizes Dr. Karle's achievements in the study of the structure of matter in vapor, crystalline, and amorphour states. For the past 34 years, including almost 32 at NRL, Dr. Karle has con ducted theoretical and experimental research in electron diffraction, x-ray diffraction, and neutron diffraction as they pertain to structural analysis of
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The Eleventh International Sympo sium on Advances in Chromatography will be held November 1-5, 1976, at the Sheraton-Houston Hotel, Hous ton, Tex. A total of 73 papers will be presented during the scientific ses sions; 31 papers are by authors from the U.S., and 42 by authors from 19 other countries. In addition to nine formal sessions, there will be six infor mal discussion groups. The technical sessions are scheduled as follows: Monday, November 1 Morning: Presentation of the M. S. Tswett Chromatography Medals; New Horizons. Afternoon: General Gas Chromatography
News Tuesday, November 2 Morning: Biochemical Gas Chromatography. Afternoon: High-Performance Thin-Layer Chromatography; Environmental Problems Wednesday, November 3 Morning: Informal discussion groups on Liquid Chromatography; GC Columns; and GC Instrumentation. Afternoon: Informal discussion groups on Environmental Problems; Biomedical GC; and High-Performance Thin-layer Chromatography. Evening: Gas Chromatography Columns and Theory Thursday, November 4 Morning: Biomedical Gas Chromatography. Afternoon: Liquid Chromatography Friday, November 5 Morning: Liquid Chromatography Further information may be obtained by writing the chairman: A. Zlatkis, Dept. of Chemistry, University of Houston, Houston, Tex. 77004.
Analytical Chemistry at Work Microparticle Analyzer A laser-excited micro-Raman spectrometer, capable of dealing with particles 1 mm in size or larger, is expected to have unique applications in environmental analysis. National Bureau of Standards scientists who developed the instrument are studying sodium sulfate, calcium sulfate, and ammonium sulfate. These particles were chosen since they are believed to have importance as particulates in air pollution. A key feature of the instrument is its optimization of detection of the very weak Raman signal from the minute particle of interest in a sample and its minimization of all other sources of interference. T h e instrument is connected to a minicomputer which permits the acquisition of data
over a long period of time. Earlier work on a design for this type of instrument proposed by Block Engineering, Inc. (Air Force contractor), demonstrated that Raman spectra could be obtained on micrometersized particles and t h a t these spectra were the same as spectra obtained from large bulk samples. T h e Raman spectra obtained with the instrument not only can be used to determine if the sulfur and oxygen are present as sulfates, sulfites, or as metal sulfides or oxides, but also provides information on the state of aggregation of the chemical units in a material, such as whether the chemical units exist in a crystalline or glass-like phase. In addition to air pollution studies, the spectrometer has potential applications in characterization of microsamples of inclusions in minerals and gems, micrometeorites, dental materials, biological specimens, and microcircuits.
Cash Award Program Announced by Electronics Firm Electronic Associates, Inc. (West Long Branch, N.J.), a leading U.S. manufacturer and designer of analog/ hybrid computer equipment, has announced a program of cash awards for doctoral-level students and educators in the area of hybrid computer technology. Its objective is to stimulate interest in the field and to encourage worldwide discussion and publication of papers presenting significant aspects of the analog/hybrid computer sciences. There are two separate activities involved in this program. One involving first, second, and third prizes of $2500, $1500, and $1000 will be awarded each year for PhD-equivalent theses or dissertations on relevant subjects. T h e other is a publication awards program for papers by university and college professors on the uses and values of hybrid computers and related technology in the curricula of engineering, science, mathematics and/or computer science. Honoraria will range from $200 to $500. Both programs will be judged and awards made by an impartial panel of educators. Further information may be obtained by writing: Arthur I. Rubin, Manager, Scientific Computation, Electronic Associates, Inc., 185 Monmouth Parkway, West Long Branch, N.J. 07764 (201-229-1100).
Greg Rosasco (foreground) looks through the eyepiece of the spectrometer to position an individual particle of interest for analysis while Edgar Etz looks on. The two NBS scientists developed the micro-Raman spectrometer from commercial components. Inset: Particles to be analyzed are mounted on the polished surface of a substrate chosen to minimize spectral interferences. Examples are sapphire, litium fluoride, or highly reflecting metallic substances
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News Caffeine in Coffee Quality control methods used by coffee makers to determine caffeine in coffee and based on continuous flow analysis with ultraviolet detection can now be speeded. The use of UV spectrophotometers with flow analysis in this application was first reported in Amsterdam in 1969 and was based on the instrumentation available at that time. Technicon's new ultraviolet spectrophotometer, which is designed specifically for use with continuous flow systems, permits analysis of 40 samples per hour. Other applications in food and agricultural areas of UV detection with continuous flow analytical systems are under development.
can be identified within minutes by comparing the unknown NMR patterns with patterns in the computer data base.
Enzyme Immunoassay Techniques Automated Enzyme immunoassay techniques for the determination of the antiepileptic drugs, diphenylhydantoin (dilantin), phénobarbital, and primidone (mysoline), have been automated for use with the KA-150 kinetic analyzer according to an application study made by Perkin-Elmer Corp. The technique, EMIT, is not new; reagents for the tests are supplied exclusively by the Syva Corp. of Palo Alto, Calif.
According to the reported study, the technique can be automated to generate reproducible data which agree with data produced by other methods. Further developments of the technique to assay other drugs or hormones present in serum at levels lower than those normally found with the antiepileptic drugs await the introduction of higher affinity antibodies and improvements in instrumentation. The enzyme immunoassay technique is similar to classical radioimmunoassay methods except that an enzyme label is used rather than a radioactive label, and the technique is homogeneous, that is, no separation of free and antibody-bound drug is required at any time.
Gold Analysis Secon Wire Div. of Secon Metals Corp. in White Plains, N.Y., has specifically prepared the Model 750 AtomComp spectrophotometer and its procedures to provide precise quantitative results in the detection of impurities in gold. Impurities in gold down to 1 ppm nominally with an accuracy as fine as ±0.5% of the reported figure can be obtained. The company's special system of the AtomComp (Jarrell-Ash Div., Fisher Scientific Co.) is programmed to quantitatively determine up to 28 elements in gold simultaneously and in any combination. The Secon system is computer controlled in the progress of the burn, in the storage of information, and in the typing of the results. For the past five years the labs have been developing gold standards to meet exact requirements, and the accuracy of these standards contributes to the overall strength of the procedure. The company offers this service to others and will supply information on the exact concentration ranges available for the impurities' elements of interest. Accurate quantitative analyses of material other than gold are under development at Secon.
Identification of Explosives Virginia Hogan, a research chemist at Picatinny Arsenal's Feltman Research Laboratory, Dover, N.J., is collating a data bank of the nuclear magnetic resonance spectra of all explosives, foreign and domestic, and military and commercial. More than 160 compounds have been tested and stored by Miss Hogan, including 120 foreign explosives. The data files will contain impurity and solvent patterns in explosive mixtures as well as the explosive patterns themselves. Once the program is computerized, materials
Jim D. Carpenter, president of Hydro-Gardens. Inc., Colorado Springs, Colo., is shown in one of the firm's hydroponic greenhouses where tomatoes are grown. The company shipped about 100 000 lb of tomatoes and 30 000 lb of cucumbers last year. Hydroponics is the growing of plants without soil; nutrients are supplied from aqueous chemical solutions. The company also markets nutrient mixtures which are analyzed by atomic absorption spectrophotometry. Varian's AA Model 1200 is used to test water supplies, measure the concentration of important elements in plant tissues, and provide assurance to customers that their plants are receiving the optimal combination of nutrients. Technicians at Hydro-Gardens analyze 50-100 samples per week. Carpenter, who is an applied chemistry graduate of Colorado State, estimates that hydroponic farmers raised about 20 million lb of tomatoes and more than 5 million lb of cucumbers last year. Less important crops include lettuce and cut flowers
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