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Antineoplastic Agents. 552. Oxidation of Combretastatin A-1: Trapping the o-Quinone Intermediate Considered the Metabolic Product of the Corresponding Phosphate Prodrug1 George R. Pettit,* Andrew J. Thornhill, Bryan R. Moser,† and Fiona Hogan Cancer Research Institute and Department of Chemistry and Biochemistry, Arizona State UniVersity, P.O. Box 872404, Tempe, Arizona 85287 ReceiVed March 21, 2008
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