Journal of Medicinal Chonistry, 1.970, T'ol. 12, S o . 3 551
NOTES
II
N-Rl Yield
R'
No. 3 4
5 6 7
a 9 10 11
12
CHI (CHdnCHa (CH?)3C H3 ( C HdsC Ha (CHdioCHs (CHz)iiCH3 (CHdiaCH3 CH(CH~~(CHP)SCH(CHS)J
0 0
hIp, CHI ( CH d ?CHI (CHI)3C H3 (CHdsCHa (CH~IOCHI (CH~IICHP (CHdiaCH3 CH(CH3j(CH2)3CH(CH3)a
0 0
13
o c
132-133 dec 114-115 dec 93-93,s 64-64.5
53.5-54.5 52,543 53-53.5 55-56
22 41 24 24 24 22
27 13
116-1 17
31
175-176
19
75-76
39
116.5-1 17
14
(56)
18
18
85-86
30
16
77-78
22
17
73-i4
21
18
83-84
24
19
61-62
33
20
6T-68
24
CaHisNnOi
21
88.5-89
as
CaH?sN?O
22
103.5-104.5
54
23
(CHz)sCH3
80-81
36
24
(CHJ)SCHI
74.5-i5
67
25
(CHdsCHa
54-55
80
123-124
63
27
103.5-104.5
46
28 29 30
a2,5-83
40 27 49
31
103-103.5
64
32
106.5-10i.5
78
26
a
C6HS
85.5-86.5 82 5 - 8 3 . 5
CPOHMN?O
C : Calcd, 79.48; Found, 79.04.
been obtained iriciderital to other chemical studies,2 while activity against Mycobacterium tuberculosis in mice has been claimed for a few other^.^ The structural (2) Cf. T. Zincke a n d E. Kiegel, Ber.. 81, 1039 (1888); L. F. Fieser and C. I
