Article Cite This: Anal. Chem. 2018, 90, 8816−8823
pubs.acs.org/ac
Ultrahigh-Resolution Mass Spectrometry in Real Time: Atmospheric Pressure Chemical Ionization Orbitrap Mass Spectrometry of Atmospheric Organic Aerosol Christoph Zuth,§ Alexander L. Vogel,‡,† Sara Ockenfeld,§ Regina Huesmann,§ and Thorsten Hoffmann*,§ §
Institute of Inorganic Chemistry and Analytical Chemistry, Johannes Gutenberg-University, Mainz 55128, Germany Laboratory for Environmental Chemistry & Laboratory for Atmospheric Chemistry, Paul Scherrer Institute, Villigen 5232, Switzerland
Anal. Chem. 2018.90:8816-8823. Downloaded from pubs.acs.org by DUQUESNE UNIV on 09/24/18. For personal use only.
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S Supporting Information *
ABSTRACT: The accurate and precise mass spectrometric measurement of organic compounds in atmospheric aerosol particles is a challenging task that requires analytical developments and adaptations of existing techniques for the atmospheric application. Here we describe the development and characterization of an atmospheric pressure chemical ionization Orbitrap mass spectrometer (APCI-Orbitrap-MS) for the measurement of organic aerosol in real time. APCI is a well-known ionization technique, featuring minimal fragmentation and matrix dependencies, and allows rapid alternation between the positive and negative ionization mode. As a proof of principle, we report ambient organic aerosol composition in real-time, with alternating ionization, high mass resolution (R = 140 000) and accuracy (
