Effect of isomers of swainsonine on glycosidase activity and glycoprotein processing. Alan D. Elbein , T. Szumilo , Barbara A. Sanford , K. Barry Shar...
Marilyn J. Schneider, Frank S. Ungemach, Harry P. Broquist, Thomas M. Harris. J. Am. Chem. Soc. , 1982, 104 (24), pp 6863â6864. DOI: 10.1021/ja00388a102.
of Health for grant support (GM-27681). Acknowledgment. We are grateful to the National Institutes. Biosynthesis of Swainsonine in Rhizoctonia leguminicola .
May 14, 2015 - N-acyliminium ions and potassium alkynyltrifluoroborates.4 In. 2012, Caprio and ... mines 7 with alkyl or aryl Grignard reagents (Figure 2, eq 1).12. Under the ..... H2O); mp 143â144 °C; lit.25a mp 143â145 °C} in 87% yield. .....
Sep 28, 2002 - The asymmetric synthesis of (â)-swainsonine via a nonchiral pool route that involves the Sharpless epoxidation to induce chirality is reported.
Sujata Bardhan, Daniel C. Schmitt, and John A. Porco, Jr. ..... Quiroz , David Corona , Adrián Covarruvias , José Gustavo Avila-Zárraga , Moisés Romero-Ortega.
The asymmetric synthesis of (-)-swainsonine via a nonchiral pool route that involves the Sharpless epoxidation to induce chirality is reported. The key steps ...
Jul 20, 2016 - (6) Ingestion of these swainsonine-containing plants causes a toxicosis in livestock leading to a chronic wasting disease, depression, altered ...
(2) Locoweed intoxication is not limited to North America; Astragalus and Oxytropis species ..... 10, 0, 0.2. mean (1â8), 0.186, 11, 4.9, 40. control, 0.193, 0.186â0.209, 0.009, 5, 5.2, 4.0â6.2, 1.0, 19 .... 1991, 27, 59â 64 ...... ACS Active
Jan 7, 2011 - Susan Hodgson , Catherine de Cates , Joshua Hodgson , Neil J. Morley , Brian C. Sutton , Alan C. Gange. Ecology and Evolution 2014 4 ...
N. Bhushan Mandava, Rodrigo G. Orellana, J. David Warthen Jr., Joseph F. Worley, Samson R. Dutky, Harold Finegold, and Billy C. Weathington. J. Agric.
6863
381 fragment
‘
C G 4 G ~ ~ C G G G l G C G C ~ l A G ~ 4 4 T l G C 4 l C 4 4 C G C 4 T A l ~ G C G C3 l A G C 4 G C 4 C G C C 4 A c G c G T A T c T T T A A c G T A G T T G c G T A T A T C G c G A T c G T c G T G c G G T 5’ i ~i GC T~ T~c~ATT Ic GC cC TGT~cPGGc CT cG G4 TGcCcIT GG GA c~ cCc~EGcGc GG c~ cG GGGCTGT GT Cc GC c4c4A~GGc Cc TG GG TlcCAGcGG A4 GC G~cGTlcGT CT G~ cCcc
J ~ P
Figure 2. Arrows indicate cleavage sites on one strand of D N A restriction fragments by DE.Fe(II).
site sizes.
Scheme I
Acknowledgment. We are grateful to the National Institutes of Health for grant support (GM-27681).
Biosynthesis of Swainsonine in Rhizoctonia leguminicola Epimerization at the Ring Fusion
