Cats' Internal Exposure to Selected Brominated Flame Retardants and

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Cats’ internal exposure to selected BFRs and organochlorines correlated to house dust and cat food Jessica Norrgran Engdahl, Anders Bignert, Bernt Jones, Ioannis Athanassiadis, Ake Bergman, and Jana Melinda Weiss Environ. Sci. Technol., Just Accepted Manuscript • DOI: 10.1021/acs.est.6b05025 • Publication Date (Web): 14 Feb 2017 Downloaded from http://pubs.acs.org on February 19, 2017

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Environmental Science & Technology

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Cats’ internal exposure to selected BFRs and organochlorines correlated to house dust and cat food

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J. Norrgran Engdahl1, A. Bignert4, B. Jones2, I. Athanassiadis1, Å. Bergman1,3, J.M. Weiss1*

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Department of Environmental Science and Analytical Chemistry, Stockholm University, SE-106 91 Stockholm, Sweden 2

Department of Clinical Sciences, Swedish University of Agricultural Sciences, SE-750 07 Uppsala, Sweden

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Swedish Toxicology Sciences Research Centre (Swetox), Forskargatan 20, SE-151 36 Södertälje, Sweden

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Swedish Museum of Natural History, Frescativägen 40, SE-114 18 Stockholm, Sweden

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Corresponding author: [email protected]

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Abstract

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Pet cats may be used as a biomarker for assessing exposures to organohalogen compounds

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(OHCs) adsorbed to household dust in home environments. This study explores two exposure

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routes of OHCs, i) ingestion of OHCs via house dust and ii) via cat food. House dust from 17

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Swedish homes and serum from the participating families’ pet cats were collected and cat food

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purchased matching the diet reported. Paired samples of cat serum, house dust, and cat food were

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analysed for brominated flame retardants/natural products (PBDEs, BB-209, DBDPE, 2,4,6-TBP,

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OH-PBDEs) and organochlorines (PCBs, DDT, DDE, HCB, PCP). Significant correlations were

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found between serum and dust samples from the living rooms for BDE-47 (p