C&EN Webinars - Characterizing traditional herbal medicines and

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WEBINARS

characterizing traditional Herbal Medicines and Herbal Supplements SEPtEMbER 30, 2014 8:00 a.m. PDT / 11:00 a.m. EDT / 16:00 BST

Stronger bonds. MODERAtOR

SPEAKERS

Ian Acworth, Director for Customer and Applications Support Termo Fisher Scientifc

Dave Tomas, Product and Support Scientist Termo Fisher Scientifc

Sophie Rovner, Assistant Managing Editor C&EN

OVERVIEW

KEy LEARnIng ObjEctIVES:

Traditional herbal medicines (THMs) and herbal supplements, sometimes called botanicals, have been used for medicinal purposes for hundreds of years to alleviate illness, improve physical appearance as well as to increase overall individual health. In recent years, growing concerns about these products include variation in levels of the purported natural product(s), authentication (whether the correct plant and part is used), possible adulteration and contamination.

Measure key analytes in TCMs and supplements

Separation and detection of key analytes in herbals can ofen be challenging due to relative abundance, structural similarity to other components and the complex nature of the matrix. Tis webinar introduces two HPLC-based approaches for the measurement of natural products in THMs and herbal supplements. Te spectro-electro array combines electrochemical and spectrophotometric detection. It is both selective and sensitive, and uses an analyte’s voltammetric and spectral properties for correct identifcation and measurement.

Learn about two novel HPLC-based approaches: spectro-electro array detection and charged aerosol detection

Charged aerosol detection is a universal approach capable of measuring any non-volatile (and many semi-volatile) analytes and produces similar inter-analyte response independent of chemical structure. Compounds do not have to possess a chromophore or need to be ionized in order to be detected. As will be discussed, these approaches can be used in a targeted way to measure levels of specifc natural products in a sample. Tey can also be used in a non-targeted (metabolomic) approach, where patterns of up to several hundred analytes (including knowns and unknowns) can be used to help authenticate product or identify possible adulteration. Finally, improvement in analytical throughput and analyte resolution using the new Termo Scientifc™ Vanquish™ UHPLC system will be presented.

REgIStER nOW or visit cen.acs.org/webinar

Evaluate product authenticity Determine adulteration Targeted and untargeted metabolomic approaches

WHO SHOULD AttEnD: Pharmacognosists Food and beverage scientists Manufacturers of herbal supplements Manufacturers of traditional medicines Pharmaceutical scientists

SPOnSOR