Correction to “Short Total Synthesis of Δ12-Prostaglandin J2 and

Feb 4, 2019 - Correction to “Short Total Synthesis of Δ12-Prostaglandin J2 and Related ... Nicholas Cen , Monette Aujay , Joseph Sandoval , Nancy Z...
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Addition/Correction Cite This: J. Org. Chem. XXXX, XXX, XXX−XXX

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Correction to “Short Total Synthesis of Δ12-Prostaglandin J2 and Related Prostaglandins. Design, Synthesis, and Biological Evaluation of Macrocyclic Δ12-Prostaglandin J2 Analogues”

K. C. Nicolaou,* Kiran Kumar Pulukuri, Stephan Rigol, Zisis Peitsinis, Ruocheng Yu, Satoshi Kishigami, Nicholas Cen, Monette Aujay, Joseph Sandoval, Nancy Zepeda, and Julia Gavrilyuk J. Org. Chem. 2019, 84 (1), 365−378. DOI: 10.1021/acs.joc.8b03057

J. Org. Chem. Downloaded from pubs.acs.org by 83.171.253.183 on 02/07/19. For personal use only.

S Supporting Information *

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properly described for compounds 14 (Schemes 2 and 4), 19 (Scheme 2), and 31 (Scheme 4). Importantly, none of the aforementioned errors has any influence on the drawn conclusions. The corrected structures and compound names are given below. We apologize for possible confusion caused by these errors. The Abstract/Table of Contents graphic and affected graphics for Figure 2 and Schemes 1−4 are shown below.

e became aware after publication of our original manuscript that the structures of compounds 5a−d in Figure 2, and of compounds 5a−d, 6a−d, and 7a−d in Schemes 1−4, respectively, have been wrongly depicted. This error also affected the Abstract graphic/Table of Contents graphic, the Supporting Information, and the names for compounds 5a−d within the Experimental Section. Last, the X substituent has not been

Scheme 2:

Figure 2:

Scheme 3: Scheme 1:

© XXXX American Chemical Society

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DOI: 10.1021/acs.joc.9b00159 J. Org. Chem. XXXX, XXX, XXX−XXX

The Journal of Organic Chemistry

Addition/Correction

Scheme 4:

Compound Names. 5a: (3aE,6S,12Z,14aS,17aE,20S,26Z,28aS)-6,20-Dipentyl-5,10,11,14,14a,19,20,23,24,25,28,28a-dodecahydro-3H,8H-dicyclopenta[e,r][1,14]dioxacyclohexacosine-3,8,17,22(6H,9H)-tetrone. 5b: (3aE,6S,12Z,14aS,17aE,20S,26Z,28aS)-2,16-Dichloro6,20-dipentyl-5,10,11,14,14a,19,20,23,24,25,28,28a-dodecahydro-3H,8H-dicyclopenta[e,r][1,14]dioxacyclohexacosine-3,8,17,22(6H,9H)-tetrone. 5c: (3aE,6S,12Z,14aS,17aE,20S,26Z,28aS)-2,16-Dichloro6,20-bis(5,5,5-trifluoropentyl)-5,10,11,14,14a,19,20,23,24,25,28,28a-dodecahydro-3H,8H-dicyclopenta[e,r][1,14]dioxacyclohexacosine-3,8,17,22(6H,9H)-tetrone. 5d: (3aE,6S,12Z,14aS,17aE,20S,26Z,28aS)-2,16-Diiodo6,20-bis(5,5,5-trifluoropentyl)-5,10,11,14,14a,19,20,23,24,25,28,28a-dodecahydro-3H,8H-dicyclopenta[e,r][1,14]dioxacyclohexacosine-3,8,17,22(6H,9H)-tetrone.



ASSOCIATED CONTENT

S Supporting Information *

The Supporting Information is available free of charge on the ACS Publications website at DOI: 10.1021/acs.joc.9b00159. Revised file containing corrected structures (PDF)

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DOI: 10.1021/acs.joc.9b00159 J. Org. Chem. XXXX, XXX, XXX−XXX