Correction to Digital Bioassays: Theory, Applications, and

Dec 1, 2017 - ACS Earth and Space Chemistry - New in 2017 · ACS Energy Letters .... Correction to Digital Bioassays: Theory, Applications, and Perspec...
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Cite This: Anal. Chem. XXXX, XXX, XXX−XXX

Correction to Digital Bioassays: Theory, Applications, and Perspectives Yi Zhang and Hiroyuki Noji* Anal. Chem. 2017, 89, 92−101. DOI: 10.1021/acs.analchem.6b04290 Details of the correction: The original manuscript contains an error in Figure 2. In the body of the figure, the letter “m” appears mistakenly in place of the correct symbol, “μ”. The correct Figure 2 appears along with the accompanying caption.

Figure 2. Concept of the digital bioassay. A schematic comparison between analog measurement and digital counting is shown. In digital bioassays (bottom part), the bulk reaction solution is partitioned into extremely small compartments to rapidly concentrate the reaction product. In conventional tube-based assays (top part), the reaction product diffuses very quickly, making a highly diluted product difficult to detect. The exemplary concentration is calculated on the basis of a microcompartment volume of 1 fL (corresponding to height, width, and depth of 1 μm).

© 2016 American Chemical Society

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DOI: 10.1021/acs.analchem.7b04754 Anal. Chem. XXXX, XXX, XXX−XXX